ING1 Antikörper (N-Term) (FITC)

Produktnummer ABIN2486912

Produktdetails anti-ING1 Antikörper (FITC)

Target: ING1 (Inhibitor of Growth Family, Member 1 (ING1))

Bindungsspezifität: N-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ING1 Antikörper ist konjugiert mit FITC

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Spezifität: Detects ~33 kDa.

Kreuzreaktivität: Human, Maus

Aufreinigung: Peptide Affinity Purified

Immunogen: Mouse p33 ING1 N-terminal peptide -KLH conjugates

Anwendungsinformationen

Applikationshinweise:

• WB (1:1000)
• ICC/IF (1:50)
• optimal dilutions for assays should be determined by the user.

Kommentare:

0.25 mg/ml was sufficient for detection of ABIN2486912 in lysates prepared from human melanoma cell lines by western blot analysis.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: TBS, 50 % glycerol, 0.01 % sodium azide, Storage buffer may change when conjugated

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Conjugated antibodies should be stored at 4°C

Details zu ING1

Target: ING1 (Inhibitor of Growth Family, Member 1 (ING1))

Andere Bezeichnung: ING1 (ING1 Produkte)

Synonyme: p24ING1c antikoerper, p33 antikoerper, p33ING1 antikoerper, p33ING1b antikoerper, p47 antikoerper, p47ING1a antikoerper, p33ING1c antikoerper, zgc:136918 antikoerper, ING1 antikoerper, 2610028J21Rik antikoerper, AA407184 antikoerper, AI875420 antikoerper, mING1h antikoerper, p33Ing1 antikoerper, p37Ing1b antikoerper, xing1 antikoerper, inhibitor of growth family member 1 antikoerper, inhibitor of growth family, member 1 antikoerper, inhibitor of growth family member 1 S homeolog antikoerper, ING1 antikoerper, Ing1 antikoerper, ing1 antikoerper, ing1.S antikoerper

Hintergrund: The p33ING1 protein encodes a 33-kD, 294-amino acid protein that displays the characteristics of a tumor suppressor gene. The p33ING1 protein is a regulator of cell cycle, senescence, and apoptosis. It can mediate growth arrest, anchor dependent growth and influence chemo sensitivity (1-4). It also has a proposed role as a growth regulator, which is consistent with its location in the nucleus (5). It has been demonstrated that the ING1 gene has three exons and that four mRNA variants are transcribed from three different promoter regions (p33 ING1, p24 ING1, p27 ING1, p47 IG1) (6, 7). ING1 can possibly influence the above biological functions depending on which variant is expressed (1-4).

Gen-ID: 26356

NCBI Accession: NP_036049

UniProt: Q9QXV3

Pathways: Protein targeting to Nucleus, Autophagie