GADD45B Antikörper

Produktnummer ABIN2463174

Produktdetails anti-GADD45B Antikörper

Target: GADD45B (Growth Arrest and DNA-Damage-Inducible, beta (GADD45B))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GADD45B Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB)

Aufreinigung: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human GADD45B.

Anwendungsinformationen

Applikationshinweise: GADD45B antibody can be used for detection of GADD45B by ELISA at 1:1562500. GADD45B antibody can be used for detection of GADD45B by western blot at 0.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Konzentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handhabung: As with any antibody avoid repeat freeze-thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: For short periods of storage (days) store at 4 °C. For longer periods of storage, store GADD45B antibody at -20 °C.

Details zu GADD45B

Target: GADD45B (Growth Arrest and DNA-Damage-Inducible, beta (GADD45B))

Andere Bezeichnung: GADD45B (GADD45B Produkte)

Synonyme: GADD45BETA antikoerper, MYD118 antikoerper, AI323528 antikoerper, Myd118 antikoerper, CS131 antikoerper, cb196 antikoerper, gadd45b antikoerper, gadd45b2 antikoerper, sb:cb196 antikoerper, zgc:73104 antikoerper, gadd45beta antikoerper, wu:fa92d10 antikoerper, wu:fa98h12 antikoerper, wu:fk65h03 antikoerper, zgc:111973 antikoerper, gadd45b1 antikoerper, gadd45bl antikoerper, zgc:112453 antikoerper, growth arrest and DNA damage inducible beta antikoerper, growth arrest and DNA-damage-inducible 45 beta antikoerper, growth arrest and DNA-damage-inducible, beta antikoerper, growth arrest and DNA-damage-inducible, beta a antikoerper, growth arrest and DNA-damage-inducible, beta b antikoerper, GADD45B antikoerper, Gadd45b antikoerper, gadd45ba antikoerper, gadd45bb antikoerper

Hintergrund: The function of GADD45B is involved in the regulation of growth and apoptosis.This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The genes in this group respond to environmental stresses by mediating activation of the p38/JNK pathway. This activation is mediated via their proteins binding and activating MTK1/MEKK4 kinase, which is an upstream activator of both p38 and JNK MAPKs. The function of these genes or their protein products is involved in the regulation of growth and apoptosis. These genes are regulated by different mechanisms, but they are often coordinately expressed and can function cooperatively in inhibiting cell growth. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Molekulargewicht: 18 kDa

Gen-ID: 4616

NCBI Accession: NP_056490

UniProt: O75293

Pathways: Zellzyklus