PTPRN
Reaktivität: Human
WB
Wirt: Maus
Polyclonal
unconjugated
Applikationshinweise
PTPRN antibody can be used for detection of PTPRN by ELISA at 1:12500. PTPRN antibody can be used for detection of PTPRN by western blot at 0.0625 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Lyophilized
Rekonstitution
Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.
Konzentration
1 mg/mL
Buffer
Antibody is lyophilized in PBS buffer with 2 % sucrose.
Handhabung
As with any antibody avoid repeat freeze-thaw cycles.
Lagerung
4 °C/-20 °C
Informationen zur Lagerung
For short periods of storage (days) store at 4 °C. For longer periods of storage, store PTPRN antibody at -20 °C.
Target
PTPRN
(Protein Tyrosine Phosphatase, Receptor Type, N (PTPRN))
IA-2 antikoerper, IA-2/PTP antikoerper, IA2 antikoerper, ICA512 antikoerper, R-PTP-N antikoerper, mIA-A antikoerper, mKIAA4064 antikoerper, Ia-2 antikoerper, fc43c04 antikoerper, ptprn antikoerper, wu:fc43c04 antikoerper, ia-2 antikoerper, ia2 antikoerper, ica512 antikoerper, r-ptp-n antikoerper, protein tyrosine phosphatase, receptor type N antikoerper, protein tyrosine phosphatase, receptor type, N antikoerper, protein tyrosine phosphatase, receptor type, Na antikoerper, protein tyrosine phosphatase, receptor type N L homeolog antikoerper, PTPRN antikoerper, Ptprn antikoerper, ptprna antikoerper, ptprn.L antikoerper
Hintergrund
PTPRN is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and a single catalytic domain, and thus represents a receptor-type PTP. This PTP was found to be an autoantigen that is reactive with insulin-dependent diabetes mellitus (IDDM) patient sera, and thus may be a potential target of autoimmunity in diabetes mellitus.