PTPRN Antikörper (Middle Region)
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- Target Alle PTPRN Antikörper anzeigen
- PTPRN (Protein Tyrosine Phosphatase, Receptor Type, N (PTPRN))
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Bindungsspezifität
- Middle Region
- Reaktivität
- Human, Ratte, Maus, Rind (Kuh), Schwein, Meerschweinchen, Kaninchen, Hund, Pferd
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser PTPRN Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Sequenz
- EVQQVPSPVS SEPPKAARPP VTPVLLEKKS PLGQSQPTVA GQPSARPAAE
- Homologie
- Cow: 86%, Dog: 100%, Guinea Pig: 85%, Horse: 93%, Human: 100%, Mouse: 100%, Pig: 86%, Rabbit: 100%, Rat: 100%
- Produktmerkmale
- This is a rabbit polyclonal antibody against PTPRN. It was validated on Western Blot using a cell lysate as a positive control.
- Aufreinigung
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human PTPRN
- Top Product
- Discover our top product PTPRN Primärantikörper
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- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
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Antigen size: 591 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- PTPRN (Protein Tyrosine Phosphatase, Receptor Type, N (PTPRN))
- Andere Bezeichnung
- PTPRN (PTPRN Produkte)
- Synonyme
- IA-2 antikoerper, IA-2/PTP antikoerper, IA2 antikoerper, ICA512 antikoerper, R-PTP-N antikoerper, mIA-A antikoerper, mKIAA4064 antikoerper, Ia-2 antikoerper, fc43c04 antikoerper, ptprn antikoerper, wu:fc43c04 antikoerper, ia-2 antikoerper, ia2 antikoerper, ica512 antikoerper, r-ptp-n antikoerper, protein tyrosine phosphatase, receptor type N antikoerper, protein tyrosine phosphatase, receptor type, N antikoerper, protein tyrosine phosphatase, receptor type, Na antikoerper, protein tyrosine phosphatase, receptor type N L homeolog antikoerper, PTPRN antikoerper, Ptprn antikoerper, ptprna antikoerper, ptprn.L antikoerper
- Hintergrund
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PTPRN is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and a single catalytic domain, and thus represents a receptor-type PTP. This PTP was found to be an autoantigen that is reactive with insulin-dependent diabetes mellitus (IDDM) patient sera, and thus may be a potential target of autoimmunity in diabetes mellitus.
Alias Symbols: FLJ16131, IA-2, IA-2/PTP, IA2, ICA512, R-PTP-N
Protein Interaction Partner: PLP1, MAL, CLN8, UBQLN4, SNX19, SPTBN4, PTPRT, MADD, PTPRS, SNTB2, NOS1, PPIA, CAPN2,
Protein Size: 889 - Molekulargewicht
- 96 kDa
- Gen-ID
- 5798
- NCBI Accession
- NM_001199763
- UniProt
- Q16849
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