Growth Hormone 2 Antikörper

Produktnummer ABIN2462514

Produktdetails anti-Growth Hormone 2 Antikörper

Target: Growth Hormone 2 (GH2)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Growth Hormone 2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Aufreinigung: Antibody is purified by protein A chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human GH2.

Anwendungsinformationen

Applikationshinweise: GH2 antibody can be used for detection of GH2 by ELISA at 1:312500. GH2 antibody can be used for detection of GH2 by western blot at 5.0 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Konzentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handhabung: As with any antibody avoid repeat freeze-thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: For short periods of storage (days) store at 4 °C. For longer periods of storage, store GH2 antibody at -20 °C.

Details zu Growth Hormone 2

Target: Growth Hormone 2 (GH2)

Andere Bezeichnung: GH2 (GH2 Produkte)

Synonyme: GH-V antikoerper, GHL antikoerper, GHV antikoerper, hGH-V antikoerper, growth hormone 2 antikoerper, GH2 antikoerper

Hintergrund: GH2 is a member of the somatotropin/prolactin family of hormones which play an important role in growth control. Mutations in its gene lead to placental growth hormone/lactogen deficiency.The protein encoded by this gene is a member of the somatotropin/prolactin family of hormones which play an important role in growth control. The gene, along with four other related genes, is located at the growth hormone locus on chromosome 17 where they are interspersed in the same transcriptional orientation, an arrangement which is thought to have evolved by a series of gene duplications. The five genes share a remarkably high degree of sequence identity. Alternative splicing generates additional isoforms of each of the five growth hormones, leading to further diversity and potential for specialization. As in the case of its pituitary counterpart, growth hormone 1, the predominant isoform of this particular family member shows similar somatogenic activity, with reduced lactogenic activity. Mutations in this gene lead to placental growth hormone/lactogen deficiency.

Molekulargewicht: 22 kDa, 25 kDa

Gen-ID: 2689

NCBI Accession: NP_072050

UniProt: O14643

Pathways: NF-kappaB Signalweg, JAK-STAT Signalweg, Response to Growth Hormone Stimulus