FZD7 Antikörper

Produktnummer ABIN2462375

Produktdetails anti-FZD7 Antikörper

Target: FZD7 (Frizzled Family Receptor 7 (FZD7))

Reaktivität: Human, Maus, Hund

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FZD7 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Aufreinigung: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human FZD7.

Anwendungsinformationen

Applikationshinweise: FZD7 antibody can be used for detection of FZD7 by ELISA at 1:1562500. FZD7 antibody can be used for detection of FZD7 by western blot at 1.0 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Konzentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handhabung: As with any antibody avoid repeat freeze-thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: For short periods of storage (days) store at 4 °C. For longer periods of storage, store FZD7 antibody at -20 °C.

Details zu FZD7

Target: FZD7 (Frizzled Family Receptor 7 (FZD7))

Andere Bezeichnung: FZD7 (FZD7 Produkte)

Synonyme: FzE3 antikoerper, Fz-7 antikoerper, Xfz7 antikoerper, frizzled-7 antikoerper, frizzled7 antikoerper, frz-7 antikoerper, frz7 antikoerper, fz7 antikoerper, fzd7-a antikoerper, fzd7-b antikoerper, fze3 antikoerper, Fz7 antikoerper, cFz-7 antikoerper, fb38g02 antikoerper, fc44b09 antikoerper, fz13 antikoerper, fz7a antikoerper, fz7b antikoerper, wu:fb38g02 antikoerper, wu:fc44b09 antikoerper, zg13 antikoerper, frizzled class receptor 7 antikoerper, frizzled class receptor 7 L homeolog antikoerper, frizzled class receptor 7b antikoerper, FZD7 antikoerper, fzd7.L antikoerper, fzd7 antikoerper, Fzd7 antikoerper, fzd7b antikoerper

Hintergrund: FZD7 is 7-transmembrane domain protein that is receptor for Wnt signaling proteins. The FZD7 protein contains an N-terminal signal sequence, 10 cysteine residues typical of the cysteine-rich extracellular domain of Fz family members, 7 putative transmembrane domains, and an intracellular C-terminal tail with a PDZ domain-binding motif.Members of the 'frizzled' gene family encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The FZD7 protein contains an N-terminal signal sequence, 10 cysteine residues typical of the cysteine-rich extracellular domain of Fz family members, 7 putative transmembrane domains, and an intracellular C-terminal tail with a PDZ domain-binding motif. FZD7 gene expression may downregulate APC function and enhance beta-catenin-mediated signals in poorly differentiated human esophageal carcinomas.

Molekulargewicht: 63 kDa

Gen-ID: 8324

NCBI Accession: NP_003498

UniProt: O75084

Pathways: WNT Signalweg, Stem Cell Maintenance