AATF Antikörper

Produktnummer ABIN2461824

Produktdetails anti-AATF Antikörper

Target: AATF (Apoptosis Antagonizing Transcription Factor (AATF))

Reaktivität: Human, Maus, Ratte, Hund

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser AATF Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Aufreinigung: Antibody is purified by protein A chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human AATF.

Anwendungsinformationen

Applikationshinweise: AATF antibody can be used for detection of AATF by ELISA at 1:312500. AATF antibody can be used for detection of AATF by western blot at 0.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Konzentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handhabung: As with any antibody avoid repeat freeze-thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: For short periods of storage (days) store at 4 °C. For longer periods of storage, store AATF antibody at -20 °C.

Details zu AATF

Target: AATF (Apoptosis Antagonizing Transcription Factor (AATF))

Andere Bezeichnung: AATF (AATF Produkte)

Synonyme: AATF antikoerper, ded antikoerper, che1 antikoerper, che-1 antikoerper, cb109 antikoerper, sb:cb109 antikoerper, wu:fc13d05 antikoerper, zgc:162071 antikoerper, CHE-1 antikoerper, CHE1 antikoerper, DED antikoerper, 4933415H02Rik antikoerper, 5830465M17Rik antikoerper, Che-1 antikoerper, Trb antikoerper, Ded antikoerper, apoptosis antagonizing transcription factor antikoerper, Apoptosis antagonizing transcription factor antikoerper, apoptosis antagonizing transcription factor S homeolog antikoerper, AATF antikoerper, aatf antikoerper, BFR2 antikoerper, NAEGRDRAFT_56916 antikoerper, Aatf antikoerper, aatf.S antikoerper

Hintergrund: The AATF gene encodes a protein that was identified on the basis of its interaction with MAP3K12/DLK, a protein kinase known to be involved in the induction of cell apoptosis. This gene product contains a leucine zipper, which is a characteristic motif of transcription factors, and was shown to exhibit strong transactivation activity when fused to Gal4 DNA binding domain. Overexpression of this gene interfered with MAP3K12 induced apoptosis.The protein encoded by this gene was identified on the basis of its interaction with MAP3K12/DLK, a protein kinase known to be involved in the induction of cell apoptosis. This gene product contains a leucine zipper, which is a characteristic motif of transcription factors, and was shown to exhibit strong transactivation activity when fused to Gal4 DNA binding domain. Overexpression of this gene interfered with MAP3K12 induced apoptosis.

Molekulargewicht: 63 kDa

Gen-ID: 26574

NCBI Accession: NP_036270

UniProt: Q9NY61

Pathways: Neurotrophin Signalübertragung, SARS-CoV-2 Protein Interaktom