DYNLL1 Antikörper

Produktnummer ABIN2459478

Produktdetails anti-DYNLL1 Antikörper

Target: DYNLL1 (Dynein, Light Chain, LC8-Type 1 (DYNLL1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DYNLL1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Aufreinigung: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human DYNLL1.

Anwendungsinformationen

Applikationshinweise: DYNLL1 antibody can be used for detection of DYNLL1 by ELISA at 1:1562500. DYNLL1 antibody can be used for detection of DYNLL1 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Konzentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handhabung: As with any antibody avoid repeat freeze-thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: For short periods of storage (days) store at 4 °C. For longer periods of storage, store DYNLL1 antibody at -20 °C.

Details zu DYNLL1

Target: DYNLL1 (Dynein, Light Chain, LC8-Type 1 (DYNLL1))

Andere Bezeichnung: DYNLL1 (DYNLL1 Produkte)

Synonyme: DLC1 antikoerper, DLC8 antikoerper, DNCL1 antikoerper, DNCLC1 antikoerper, LC8 antikoerper, LC8a antikoerper, PIN antikoerper, hdlc1 antikoerper, dynll2 antikoerper, wu:fd56c09 antikoerper, zgc:73406 antikoerper, Dlc8 antikoerper, Dnclc1 antikoerper, Pin antikoerper, 8kDLC antikoerper, lc8 antikoerper, dlc1 antikoerper, dlc8 antikoerper, lc8a antikoerper, dncl1 antikoerper, dnclc1 antikoerper, dynll1a antikoerper, MGC68763 antikoerper, CDLC2 antikoerper, dynll1 antikoerper, dynll1b antikoerper, pin antikoerper, MGC89636 antikoerper, dynein light chain LC8-type 1 antikoerper, dynein, light chain, LC8-type 1 antikoerper, dynein light chain LC8-type 1 S homeolog antikoerper, dynein light chain LC8-type 1 L homeolog antikoerper, Dynein light chain 1, cytoplasmic antikoerper, DYNLL1 antikoerper, dynll1 antikoerper, Dynll1 antikoerper, dynll1.S antikoerper, dynll1.L antikoerper, dlc-1 antikoerper

Hintergrund: Cytoplasmic dyneins are large enzyme complexes with a molecular mass of about 1,200 kD. They contain two force-producing heads formed primarily from dynein heavy chains, and stalks linking the heads to a basal domain, which contains a varying number of accessory intermediate chains. The complex is involved in intracellular transport and motility. DYNLL1 is a light chain and exists as part of this complex but also physically interacts with and inhibits the activity of neuronal nitric oxide synthase. Binding of this protein destabilizes the neuronal nitric oxide synthase dimer, a conformation necessary for activity, and it may regulate numerous biologic processes through its effects on nitric oxide synthase activity.Cytoplasmic dyneins are large enzyme complexes with a molecular mass of about 1,200 kD. They contain two force-producing heads formed primarily from dynein heavy chains, and stalks linking the heads to a basal domain, which contains a varying number of accessory intermediate chains. The complex is involved in intracellular transport and motility. The protein described in this record is a light chain and exists as part of this complex but also physically interacts with and inhibits the activity of neuronal nitric oxide synthase. Binding of this protein destabilizes the neuronal nitric oxide synthase dimer, a conformation necessary for activity, and it may regulate numerous biologic processes through its effects on nitric oxide synthase activity. Alternate transcriptional splice variants have been characterized.

Molekulargewicht: 10 kDa

Gen-ID: 8655

NCBI Accession: NP_001032583

UniProt: P63167

Pathways: M Phase, Tube Formation, Positive Regulation of Endopeptidase Activity