NR1H3 Antikörper

Produktnummer ABIN2458329

Produktdetails anti-NR1H3 Antikörper

Target: NR1H3 (Nuclear Receptor Subfamily 1, Group H, Member 3 (NR1H3))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NR1H3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Aufreinigung: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human NR1H3.

Anwendungsinformationen

Applikationshinweise: NR1H3 antibody can be used for detection of NR1H3 by ELISA at 1:62500. NR1H3 antibody can be used for detection of NR1H3 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Konzentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handhabung: As with any antibody avoid repeat freeze-thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: For short periods of storage (days) store at 4 °C. For longer periods of storage, store NR1H3 antibody at -20 °C.

Details zu NR1H3

Target: NR1H3 (Nuclear Receptor Subfamily 1, Group H, Member 3 (NR1H3))

Andere Bezeichnung: NR1H3 (NR1H3 Produkte)

Synonyme: NR1H3 antikoerper, LXR-a antikoerper, LXRA antikoerper, RLD-1 antikoerper, AU018371 antikoerper, LXR antikoerper, RLD1 antikoerper, Unr1 antikoerper, LXRalpha antikoerper, LXR-alpha antikoerper, im:7141239 antikoerper, wu:fd59b01 antikoerper, zgc:113339 antikoerper, zgc:158542 antikoerper, nuclear receptor subfamily 1 group H member 3 antikoerper, nuclear receptor subfamily 1, group H, member 3 antikoerper, NR1H3 antikoerper, nr1h3 antikoerper, Nr1h3 antikoerper

Hintergrund: Interaction of NR1H3 with RXR shifts RXR from its role as a silent DNA-binding partner to an active ligand-binding subunit in mediating retinoid responses through target genes defined by LXRES. NR1H3 are DR4-type response elements characterized by direct repeats of two similar hexanuclotide half-sites spaced by four nucleotides. NR1H3 Plays an important role in the regulation of cholesterol homeostasis.

Molekulargewicht: 50 kDa

Gen-ID: 10062

NCBI Accession: NP_005684

UniProt: Q13133

Pathways: Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Nuclear Hormone Receptor Binding, Cellular Response to Molecule of Bacterial Origin, Hepatitis C