TARDBP Antikörper

Produktnummer ABIN2458178

Produktdetails anti-TARDBP Antikörper

Target: TARDBP (TAR DNA Binding Protein (TARDBP))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TARDBP Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Aufreinigung: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human TARDBP.

Anwendungsinformationen

Applikationshinweise: TARDBP antibody can be used for detection of TARDBP by ELISA at 1:12500. TARDBP antibody can be used for detection of TARDBP by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Konzentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handhabung: As with any antibody avoid repeat freeze-thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: For short periods of storage (days) store at 4 °C. For longer periods of storage, store TARDBP antibody at -20 °C.

Details zu TARDBP

Target: TARDBP (TAR DNA Binding Protein (TARDBP))

Andere Bezeichnung: TARDBP (TARDBP Produkte)

Synonyme: TARDBP antikoerper, TDP43 antikoerper, DKFZp459I2127 antikoerper, tardbp antikoerper, ALS10 antikoerper, TDP-43 antikoerper, 1190002A23Rik antikoerper, C85084 antikoerper, Tdp43 antikoerper, wu:fb77f02 antikoerper, wu:fc52g10 antikoerper, TAR DNA binding protein antikoerper, Tardbp protein antikoerper, TAR DNA binding protein L homeolog antikoerper, TAR DNA-binding protein 43-like antikoerper, TARDBP antikoerper, tardbp antikoerper, tardbp.L antikoerper, Tardbp antikoerper, LOC100621383 antikoerper

Hintergrund: HIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome that produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expression by the transactivator Tat is dependent on an RNA regulatory element (TAR) located downstream of the transcription initiation site. TARDBP is a transcriptional repressor that binds to chromosomally integrated TAR DNA and represses HIV-1 transcription.HIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome that produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expression by the transactivator Tat is dependent on an RNA regulatory element (TAR) located downstream of the transcription initiation site. The protein encoded by this gene is a transcriptional repressor that binds to chromosomally integrated TAR DNA and represses HIV-1 transcription. In addition, this protein regulates alternate splicing of the CFTR gene. A similar pseudogene is present on chromosome 20. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Molekulargewicht: 45 kDa

Gen-ID: 23435

NCBI Accession: NP_031401

UniProt: Q13148

Pathways: Positive Regulation of Peptide Hormone Secretion