TARDBP Antikörper (AA 1-260)
Kurzübersicht für TARDBP Antikörper (AA 1-260) (ABIN3021656)
Target
Alle TARDBP Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 1-260
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Sequenz
- MSEYIRVTED ENDEPIEIPS EDDGTVLLST VTAQFPGACG LRYRNPVSQC MRGVRLVEGI LHAPDAGWGN LVYVVNYPKD NKRKMDETDA SSAVKVKRAV QKTSDLIVLG LPWKTTEQDL KEYFSTFGEV LMVQVKKDLK TGHSKGFGFV RFTEYETQVK VMSQRHMIDG RWCDCKLPNS KQSQDEPLRS RKVFVGRCTE DMTEDELREF FSQYGDVMDV FIPKPFRAFA FVTFADDQIA QSLCGEDLII KGISVHISNA
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Kreuzreaktivität
- Human, Maus, Ratte
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Produktmerkmale
- Polyclonal Antibodies
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Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human TDP-43/TARDB (NP_031401.1).
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Isotyp
- IgG
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anti-TAR DNA Binding Protein (TARDBP) (AA 1-260) antibody
TARDBP Reaktivität: Human WB, IF, ELISA, IP, IHC (p), RNAi Wirt: Maus Monoclonal 2E2-D3 unconjugated
anti-TAR DNA Binding Protein (TARDBP) (AA 104-262) antibodyTARDBP Reaktivität: Human WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-TAR DNA Binding Protein (TARDBP) antibodyTARDBP Reaktivität: Human WB, IHC, IF Wirt: Kaninchen Monoclonal unconjugated
anti-TAR DNA Binding Protein (TARDBP) antibodyTARDBP Reaktivität: Human WB, IHC, ELISA, ICC, FACS Wirt: Maus Monoclonal 6G2D8 unconjugated
anti-TAR DNA Binding Protein (TARDBP) (C-Term) antibodyTARDBP Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Pferd, Meerschweinchen WB, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-TAR DNA Binding Protein (TARDBP) (AA 1-100) antibodyTARDBP Reaktivität: Human WB, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-TAR DNA Binding Protein (TARDBP) antibodyKD Validated TARDBP Reaktivität: Human WB, FACS, IF (p) Wirt: Kaninchen Monoclonal 23GB4730 unconjugated Recombinant Antibody
anti-TAR DNA Binding Protein (TARDBP) antibodyKO Validated TARDBP Reaktivität: Human WB, IF, ICC, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-TAR DNA Binding Protein (TARDBP) (N-Term) antibodyTARDBP Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Pferd, Meerschweinchen WB, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-TAR DNA Binding Protein (TARDBP) (AA 1-261) antibodyTARDBP Reaktivität: Human WB, IHC, IF, ELISA, IHC (p), RNAi Wirt: Maus Monoclonal 2E2-D3 unconjugated
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Applikationshinweise
- WB,1:500 - 1:2000,IP,1:50 - 1:100,RIP,1:20 - 1:50
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid freeze / thaw cycles
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- TARDBP (TAR DNA Binding Protein (TARDBP))
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Andere Bezeichnung
- TARDBP
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Hintergrund
- HIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome that produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expression by the transactivator Tat is dependent on an RNA regulatory element (TAR) located downstream of the transcription initiation site. The protein encoded by this gene is a transcriptional repressor that binds to chromosomally integrated TAR DNA and represses HIV-1 transcription. In addition, this protein regulates alternate splicing of the CFTR gene. A similar pseudogene is present on chromosome 20.,ALS10,TDP-43,TARDBP,TDP43,Epigenetics & Nuclear Signaling,RNA Binding,Cell Biology & Developmental Biology,Apoptosis,Neuroscience,Neurodegenerative Diseases,Neurodegenerative Diseases Markers,Other Neurological disorders,Amyotrophic lateral sclerosis-ALS,TARDBP
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Molekulargewicht
- 31 kDa/44 kDa
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Gen-ID
- 23435
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UniProt
- Q13148
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Pathways
- Positive Regulation of Peptide Hormone Secretion
Target
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