CHRNA4 Antikörper

Produktnummer ABIN2458123

Produktdetails anti-CHRNA4 Antikörper

Target: CHRNA4 (Cholinergic Receptor, Nicotinic, alpha 4 (CHRNA4))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CHRNA4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Aufreinigung: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human CHRNA4.

Anwendungsinformationen

Applikationshinweise: CHRNA4 antibody can be used for detection of CHRNA4 by ELISA at 1:62500. CHRNA4 antibody can be used for detection of CHRNA4 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Konzentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handhabung: As with any antibody avoid repeat freeze-thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: For short periods of storage (days) store at 4 °C. For longer periods of storage, store CHRNA4 antibody at -20 °C.

Details zu CHRNA4

Target: CHRNA4 (Cholinergic Receptor, Nicotinic, alpha 4 (CHRNA4))

Andere Bezeichnung: CHRNA4 (CHRNA4 Produkte)

Synonyme: NACHRA4 antikoerper, BFNC antikoerper, EBN antikoerper, EBN1 antikoerper, NACHR antikoerper, NACRA4 antikoerper, NARAC antikoerper, Acra-4 antikoerper, Acra4 antikoerper, ENFL1 antikoerper, neuronal acetylcholine receptor subunit alpha-4 antikoerper, neuronal acetylcholine receptor subunit alpha-4-like antikoerper, cholinergic receptor nicotinic alpha 4 subunit antikoerper, cholinergic receptor, nicotinic, alpha 4b antikoerper, cholinergic receptor, nicotinic, alpha polypeptide 4 antikoerper, CpipJ_CPIJ002434 antikoerper, LOC100368057 antikoerper, CHRNA4 antikoerper, chrna4b antikoerper, Chrna4 antikoerper

Hintergrund: CHRNA4 is a nicotinic acetylcholine receptor, which belongs to a superfamily of ligand-gated ion channels that play a role in fast signal transmission at synapses. These pentameric receptors can bind acetylcholine, which causes an extensive change in conformation that leads to the opening of an ion-conducting channel across the plasma membrane. This protein is an integral membrane receptor subunit that can interact with either nAChR beta-2 or nAChR beta-4 to form a functional receptor. Mutations in this gene cause nocturnal frontal lobe epilepsy type 1. Polymorphisms in this gene that provide protection against nicotine addiction have been described. This gene encodes a nicotinic acetylcholine receptor, which belongs to a superfamily of ligand-gated ion channels that play a role in fast signal transmission at synapses. These pentameric receptors can bind acetylcholine, which causes an extensive change in conformation that leads to the opening of an ion-conducting channel across the plasma membrane. This protein is an integral membrane receptor subunit that can interact with either nAChR beta-2 or nAChR beta-4 to form a functional receptor. Mutations in this gene cause nocturnal frontal lobe epilepsy type 1. Polymorphisms in this gene that provide protection against nicotine addiction have been described. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Molekulargewicht: 67 kDa

Gen-ID: 1137

NCBI Accession: NP_000735

UniProt: P43681

Pathways: Synaptic Membrane