ZFPM1 Antikörper

Produktnummer ABIN2457936

Produktdetails anti-ZFPM1 Antikörper

Target: ZFPM1 (Zinc Finger Protein, Multitype 1 (ZFPM1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ZFPM1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Aufreinigung: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human ZFPM1.

Anwendungsinformationen

Applikationshinweise: ZFPM1 antibody can be used for detection of ZFPM1 by ELISA at 1:62500. ZFPM1 antibody can be used for detection of ZFPM1 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Konzentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handhabung: As with any antibody avoid repeat freeze-thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: For short periods of storage (days) store at 4 °C. For longer periods of storage, store ZFPM1 antibody at -20 °C.

Details zu ZFPM1

Target: ZFPM1 (Zinc Finger Protein, Multitype 1 (ZFPM1))

Andere Bezeichnung: ZFPM1 (ZFPM1 Produkte)

Synonyme: FOG antikoerper, FOG1 antikoerper, ZC2HC11A antikoerper, ZNF408 antikoerper, ZNF89A antikoerper, Fog1 antikoerper, Xfog antikoerper, fog antikoerper, fog-1 antikoerper, fog1 antikoerper, FOG-1 antikoerper, si:dkey-20g6.1 antikoerper, si:dkey-38l12.1 antikoerper, ZNF469 antikoerper, ZFPM1 antikoerper, zinc finger protein, FOG family member 1 antikoerper, zinc finger protein, multitype 1 antikoerper, zinc finger protein, FOG family member 1 L homeolog antikoerper, ZFPM1 antikoerper, Zfpm1 antikoerper, zfpm1.L antikoerper, zfpm1 antikoerper

Hintergrund: ZFPM1 is a transcription regulator that plays an essential role in erythroid and megakaryocytic cell differentiation. ZFPM1 is an essential cofactor that acts via the formation of a heterodimer with transcription factors of the GATA family GATA1, GATA2 and GATA3. Such heterodimer can both activate or repress transcriptional activity, depending on the cell and promoter context. The heterodimer formed with GATA proteins is essential to activate expression of genes such as NFE2, ITGA2B, alpha- and beta-globin, while it represses expression of KLF1. ZFPM1 may be involved in regulation of some genes in gonads. ZFPM1 may also be involved in cardiac development, in a non-redundant way with ZFPM2/FOG2.

Molekulargewicht: 105 kDa

Gen-ID: 161882

NCBI Accession: NP_722520

UniProt: Q8IX07