TP53INP1 Antikörper

Produktnummer ABIN2435140

Produktdetails anti-TP53INP1 Antikörper

Target: TP53INP1 (Tumor Protein P53 Inducible Nuclear Protein 1 (TP53INP1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TP53INP1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Aufreinigung: Affinity purification

Immunogen: Synthetic peptide of human TP53INP1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:200-1:1000, IHC 1:50-1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Konservierungsmittel: Sodium azide

Handhabung: Avoid freeze / thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu TP53INP1

Target: TP53INP1 (Tumor Protein P53 Inducible Nuclear Protein 1 (TP53INP1))

Andere Bezeichnung: TP53INP1 (TP53INP1 Produkte)

Synonyme: cb1036 antikoerper, wu:fb70a09 antikoerper, wu:fi13h08 antikoerper, zgc:158431 antikoerper, TP53INP1 antikoerper, 2700057G22Rik antikoerper, SIP antikoerper, SIP18 antikoerper, SIP27 antikoerper, Stinp antikoerper, Teap antikoerper, TP53DINP1 antikoerper, TP53INP1A antikoerper, TP53INP1B antikoerper, p53DINP1 antikoerper, Trp53inp1 antikoerper, tumor protein p53 inducible nuclear protein 1 antikoerper, tumor protein p53 inducible nuclear protein 1 S homeolog antikoerper, transformation related protein 53 inducible nuclear protein 1 antikoerper, TP53INP1 antikoerper, tp53inp1.S antikoerper, tp53inp1 antikoerper, Trp53inp1 antikoerper, Tp53inp1 antikoerper

Hintergrund: TP53INP1 (tumor protein p53-inducible nuclear protein 1), also known as p53DINP1, SIP or Teap, is a 240 amino acid protein that localizes to nuclear bodies and exists as two alternatively spliced isoforms, designated p53DINP1a and p53DINP1b. Expressed ubiquitously with higher expression in testis, pancreas and spleen tissue, TP53INP1 functions in response to double-stranded DNA breaks and regulates p53-mediated apoptosis, specifically by phosphorylating human p53 at Ser 46, an event that leads to cell death. Additionally, TP53INP1 is thought to interact with p73 and may be involved in the regulation of p73-controlled cell cycle progression. TP53INP1 expression is downregulated in pancreatic ductal adenocarcinomas, suggesting that, via its ability to induce cell death, TP53INP1 plays a role in tumor suppression.

Molekulargewicht: Calculated MW: 27 kDa

NCBI Accession: NP_150601