Caspase 2 Antikörper

Produktnummer ABIN2427572

Produktdetails anti-Caspase 2 Antikörper

Target: Caspase 2 (CASP2) (Caspase 2, Apoptosis-Related Cysteine Peptidase (CASP2))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Caspase 2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Aufreinigung: Affinity purification

Immunogen: Recombinant protein of human CASP2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:1000-1:2000, IHC 1:100-1:300

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.6 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Konservierungsmittel: Sodium azide

Handhabung: Avoid freeze / thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu Caspase 2

Target: Caspase 2 (CASP2) (Caspase 2, Apoptosis-Related Cysteine Peptidase (CASP2))

Andere Bezeichnung: CASP2 (CASP2 Produkte)

Synonyme: xCaspase-2 antikoerper, Caspase-2 antikoerper, ICH-1 antikoerper, Nedd2 antikoerper, CASP-2 antikoerper, ICH1 antikoerper, NEDD-2 antikoerper, NEDD2 antikoerper, PPP1R57 antikoerper, ICH-1L/1S antikoerper, ICH1L1S antikoerper, caspase 2 antikoerper, caspase 2 L homeolog antikoerper, caspase-2 antikoerper, CASP2 antikoerper, casp2.L antikoerper, CpipJ_CPIJ008254 antikoerper, Casp2 antikoerper

Hintergrund: This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Caspases mediate cellular apoptosis through the proteolytic cleavage of specific protein substrates. The encoded protein may function in stress-induced cell death pathways, cell cycle maintenance, and the suppression of tumorigenesis. Increased expression of this gene may play a role in neurodegenerative disorders including Alzheimer's disease, Huntington's disease and temporal lobe epilepsy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Molekulargewicht: Calculated MW: 51 kDa

Pathways: Apoptose, Caspase Kaskade in der Apoptose, Neurotrophin Signalübertragung