Caspase 2 Antikörper (AA 198-226)

Produktnummer ABIN3030295

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch Caspase 2 in WB, ELISA, IHC und FACS. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für Caspase 2 Antikörper (AA 198-226) (ABIN3030295)

Target: Caspase 2 (CASP2) (Caspase 2, Apoptosis-Related Cysteine Peptidase (CASP2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Caspase 2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS)

Produktdetails anti-Caspase 2 Antikörper

Bindungsspezifität: AA 198-226

Aufreinigung: Purified

Immunogen: A portion of amino acids 198-226 from the human protein was used as the immunogen for this Caspase-2 antibody.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Titration of the Caspase-2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:10-1:50,Flow Cytometry: 1:10-1:50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: In 1X PBS pH 7.4 with 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the Caspase-2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Details zu Caspase 2

Target: Caspase 2 (CASP2) (Caspase 2, Apoptosis-Related Cysteine Peptidase (CASP2))

Andere Bezeichnung: Caspase-2

Hintergrund: CASP2 is a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. The protein exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. The proteolytic cleavage of this protein is induced by a variety of apoptotic stimuli.

UniProt: P42575

Pathways: Apoptose, Caspase Kaskade in der Apoptose, Neurotrophin Signalübertragung