cb984 antikoerper, ptprm antikoerper, zgc:110218 antikoerper, PTPRM antikoerper, p-ptp-mu antikoerper, ptprl1 antikoerper, r-ptpu antikoerper, rptpm antikoerper, rptpu antikoerper, PTPRL1 antikoerper, R-PTP-MU antikoerper, RPTPM antikoerper, RPTPU antikoerper, hR-PTPu antikoerper, RPTPmu antikoerper, mKIAA4044 antikoerper, protein tyrosine phosphatase, receptor type, M, a antikoerper, protein tyrosine phosphatase, receptor type M antikoerper, protein tyrosine phosphatase, receptor type, M, b antikoerper, receptor-type tyrosine-protein phosphatase mu antikoerper, protein tyrosine phosphatase, receptor type, M antikoerper, ptprma antikoerper, PTPRM antikoerper, ptprmb antikoerper, ptprm antikoerper, LOC100550127 antikoerper, LOC100564083 antikoerper, Ptprm antikoerper
Hintergrund
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and two tandem catalytic domains, and thus represents a receptor-type PTP. The extracellular region contains a meprin-A5 antigen-PTP mu (MAM) domain, an Ig-like domain and four fibronectin type III-like repeats. This PTP has been shown to mediate cell-cell aggregation through the interaction with another molecule of this PTP on an adjacent cell. This PTP can interact with scaffolding protein RACK1/GNB2L1, whicHuman, Mouseay be necessary for the downstream signaling in response to cell-cell adhesion. Alternative splicing results in multiple transcripts encoding distinct isoforms.