PTPRM Antikörper

Produktnummer ABIN7238327

Produktdetails anti-PTPRM Antikörper

Target: PTPRM (Protein Tyrosine Phosphatase, Receptor Type, M (PTPRM))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PTPRM Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC)

Produktmerkmale: Polyclonal Antibody

Aufreinigung: Affinity purification

Immunogen: Synthetic peptide of human PTPRM

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC 1:50-1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.4 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu PTPRM

Target: PTPRM (Protein Tyrosine Phosphatase, Receptor Type, M (PTPRM))

Andere Bezeichnung: PTPRM (PTPRM Produkte)

Synonyme: cb984 antikoerper, ptprm antikoerper, zgc:110218 antikoerper, PTPRM antikoerper, p-ptp-mu antikoerper, ptprl1 antikoerper, r-ptpu antikoerper, rptpm antikoerper, rptpu antikoerper, PTPRL1 antikoerper, R-PTP-MU antikoerper, RPTPM antikoerper, RPTPU antikoerper, hR-PTPu antikoerper, RPTPmu antikoerper, mKIAA4044 antikoerper, protein tyrosine phosphatase, receptor type, M, a antikoerper, protein tyrosine phosphatase, receptor type M antikoerper, protein tyrosine phosphatase, receptor type, M, b antikoerper, receptor-type tyrosine-protein phosphatase mu antikoerper, protein tyrosine phosphatase, receptor type, M antikoerper, ptprma antikoerper, PTPRM antikoerper, ptprmb antikoerper, ptprm antikoerper, LOC100550127 antikoerper, LOC100564083 antikoerper, Ptprm antikoerper

Hintergrund: The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and two tandem catalytic domains, and thus represents a receptor-type PTP. The extracellular region contains a meprin-A5 antigen-PTP mu (MAM) domain, an Ig-like domain and four fibronectin type III-like repeats. This PTP has been shown to mediate cell-cell aggregation through the interaction with another molecule of this PTP on an adjacent cell. This PTP can interact with scaffolding protein RACK1/GNB2L1, whicHuman, Mouseay be necessary for the downstream signaling in response to cell-cell adhesion. Alternative splicing results in multiple transcripts encoding distinct isoforms.

NCBI Accession: NP_002836

UniProt: P28827