PTPRM Antikörper (AA 565-742)
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- Target Alle PTPRM Antikörper anzeigen
- PTPRM (Protein Tyrosine Phosphatase, Receptor Type, M (PTPRM))
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Bindungsspezifität
- AA 565-742
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser PTPRM Antikörper ist unkonjugiert
- Applikation
- ELISA, Immunohistochemistry (IHC), Western Blotting (WB), Immunocytochemistry (ICC), Flow Cytometry (FACS), Neutralization (Neut)
- Aufreinigung
- purified
- Immunogen
- Purified recombinant fragment of human PTPRM (AA: extra 565-742) expressed in E. coli.
- Klon
- 8F1C10
- Isotyp
- IgG1
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- Applikationshinweise
- ELISA: 1:10000, WB: 1:500 - 1:2000, ICC: N/A, FCM: N/A, IHC: N/A
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- Purified antibody in PBS with 0.05 % sodium azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
- 4°C, -20°C for long term storage
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- Target
- PTPRM (Protein Tyrosine Phosphatase, Receptor Type, M (PTPRM))
- Andere Bezeichnung
- PTPRM (PTPRM Produkte)
- Synonyme
- cb984 antikoerper, ptprm antikoerper, zgc:110218 antikoerper, PTPRM antikoerper, p-ptp-mu antikoerper, ptprl1 antikoerper, r-ptpu antikoerper, rptpm antikoerper, rptpu antikoerper, PTPRL1 antikoerper, R-PTP-MU antikoerper, RPTPM antikoerper, RPTPU antikoerper, hR-PTPu antikoerper, RPTPmu antikoerper, mKIAA4044 antikoerper, protein tyrosine phosphatase, receptor type, M, a antikoerper, protein tyrosine phosphatase, receptor type M antikoerper, protein tyrosine phosphatase, receptor type, M, b antikoerper, receptor-type tyrosine-protein phosphatase mu antikoerper, protein tyrosine phosphatase, receptor type, M antikoerper, ptprma antikoerper, PTPRM antikoerper, ptprmb antikoerper, ptprm antikoerper, LOC100550127 antikoerper, LOC100564083 antikoerper, Ptprm antikoerper
- Hintergrund
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Description: The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and two tandem catalytic domains, and thus represents a receptor-type PTP. The extracellular region contains a meprin-A5 antigen-PTP mu (MAM) domain, an Ig-like domain and four fibronectin type III-like repeats. This PTP has been shown to mediate cell-cell aggregation through the interaction with another molecule of this PTP on an adjacent cell. This PTP can interact with scaffolding protein RACK1/GNB2L1, which may be necessary for the downstream signaling in response to cell-cell adhesion. Alternative splicing results in multiple transcripts encoding distinct isoforms.
Aliases: RPTPM, RPTPU, PTPRL1, hR-PTPu, R-PTP-MU
- Molekulargewicht
- 163.7 kDa
- Gen-ID
- 5797
- HGNC
- 2215
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