CDK9 Antikörper (pThr29)

Produktnummer ABIN233827

Produktdetails anti-CDK9 Antikörper

Target: CDK9 (Cyclin-Dependent Kinase 9 (CDK9))

Bindungsspezifität: pThr29

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CDK9 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Kreuzreaktivität: Maus, Ratte (Rattus)

Produktmerkmale: Concentration Definition: by UV absorbance at 280 nm

Immunogen: This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to residues surrounding T29 in the human CDK9 protein.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: This affinity purified antibody has been tested for use in ELISA and western blotting.  Specific conditions for reactivity should be optimized by the end user.  Expect a band approximately 42 kDa in size corresponding to phosphorylated CDK9 protein by western blotting in the appropriate cell lysate or extract.  This phospho-specific polyclonal antibody reacts with human CDK9 pT29 and shows minimal reactivity by ELISA against the non-phosphorylated form of the immunizing peptide.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1.3 mg/mL

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Details zu CDK9

Target: CDK9 (Cyclin-Dependent Kinase 9 (CDK9))

Andere Bezeichnung: CDK9 (CDK9 Produkte)

Synonyme: C-2k antikoerper, CDC2L4 antikoerper, CTK1 antikoerper, PITALRE antikoerper, TAK antikoerper, wu:fb22e09 antikoerper, wu:fc06c02 antikoerper, c-2k antikoerper, cdc2l4 antikoerper, cdk9 antikoerper, ctk1 antikoerper, pitalre antikoerper, tak antikoerper, CDK9 antikoerper, CG5179 antikoerper, Dmel\\CG5179 antikoerper, P-TEF antikoerper, P-TEFb antikoerper, PTefb antikoerper, cyclin dependent kinase 9 antikoerper, cyclin-dependent kinase 9 (CDC2-related kinase) antikoerper, cyclin-dependent kinase 9 L homeolog antikoerper, cyclin-dependent kinase 9 antikoerper, Cyclin-dependent kinase 9 antikoerper, cyclin-dependent kinase 9 S homeolog antikoerper, CDK9 antikoerper, cdk9 antikoerper, cdk9.L antikoerper, Cdk9 antikoerper, cdk9.S antikoerper

Hintergrund: This antibody is designed, produced, and is suitable for Cancer, Immunology and Nuclear Signaling research. CDK9 (PITALRE) (also known as cyclin-dependent kinase 9, Serine/threonine-protein kinase PITALRE, C-2K and Cell division cycle 2-like protein kinase 4) is a member of the cyclin-dependent protein kinase (CDK) family.  CDK family members are highly similar to the gene products of S. cerevisiae cdc28 and S. pombe cdc2 and are known as important cell cycle regulators.  CDK9 (PITALRE) interacts with a conserved domain in the TRAF-C region of the tumor necrosis factor signal transducer TRAF2.  This kinase was also found to be a component of the multiprotein complex TAK/P-TEFb, which is an elongation factor for RNA polymerase II-directed transcription and functions by phosphorylating the C-terminal domain of the largest subunit of RNA polymerase II.  This protein forms a complex with, and is regulated by, its regulatory subunit, cyclin T or cyclin K. HIV-1 Tat protein
Synonyms: Cell division protein kinase 9 Cyclin-dependent kinase 9 Serine/threonine-protein kinase PITALRE Cell division cycle 2-like protein kinase 4 C-2K

Gen-ID: 1025, 4502747

UniProt: P50750

Pathways: Zellzyklus