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PVRL2 Antikörper (Poliovirus Receptor-Related 2 (Herpesvirus Entry Mediator B)) (FITC) Primary Antibody

PVRL2 Reaktivität: Maus IA, IHC (fro), FACS, IP, WB Wirt: Ratte Monoclonal 502-57 FITC
Pubmed (2 Referenzen)
Produktnummer ABIN2191801
$885.41
Zzgl. Versandkosten $45.00
100 μg
Lieferung in 6 bis 8 Werktagen
  • Target Alle PVRL2 Antikörper anzeigen
    PVRL2
    Reaktivität
    • 69
    • 20
    • 9
    • 2
    • 1
    Maus
    Wirt
    • 50
    • 13
    • 11
    Ratte
    Klonalität
    • 43
    • 31
    Monoklonal
    Konjugat
    • 38
    • 5
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser PVRL2 Antikörper ist konjugiert mit FITC
    Applikation
    • 40
    • 34
    • 18
    • 17
    • 16
    • 14
    • 14
    • 11
    • 7
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    Immunoassay (IA), Immunohistochemistry (Frozen Sections) (IHC (fro)), Flow Cytometry (FACS), Immunoprecipitation (IP), Western Blotting (WB)
    Klon
    502-57
  • Applikationshinweise
    For flow cytometry, Western blotting and immunohistology dilutions to be used depend on detection system applied. It is recommended that users test the reagent and determine their own optimal dilutions. The typical starting working dilution is 1:10. Fixation with PFA or acetone/methanol is recommended.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Buffer
    PBS, containing 0.1 % bovine serum albumin and 0.02 % sodium azide.
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C
    Informationen zur Lagerung
    Product should be stored at 4 °C. Under recommended storage conditions, product is stable for one year.
    Haltbarkeit
    12 months
  • Kawabe, Nakanishi, Asada, Fukuhara, Morimoto, Takeuchi, Takai: "Pilt, a novel peripheral membrane protein at tight junctions in epithelial cells." in: The Journal of biological chemistry, Vol. 276, Issue 51, pp. 48350-5, (2001) (PubMed).

    Sakisaka, Nakanishi, Takahashi, Mandai, Miyahara, Satoh, Takaishi, Takai: "Different behavior of l-afadin and neurabin-II during the formation and destruction of cell-cell adherens junction." in: Oncogene, Vol. 18, Issue 8, pp. 1609-17, (1999) (PubMed).

  • Target
    PVRL2
    Andere Bezeichnung
    Nectin-2 (PVRL2 Produkte)
    Synonyme
    prr2, AI325026, AI987993, Cd112, MPH, Pvr, Pvs, nectin-2, CD112, HVEB, PRR2, PVRR2, nectin cell adhesion molecule 2, Nectin2, NECTIN2
    Hintergrund
    Nectin (originally isolated as poliovirus receptor-related protein (PRR)) is a cell-cell adhesion molecule of the immunoglobulin supergene family. Nectin is colocalized with afadin at cadherin-based cell-cell adherence junctions in various tissues and cell lines. The nectin family consist of nectin-1, nectin-2 and nectin-3. Nectin-2 also known as PRR2 or CD112 is a plasma membrane adhesion molecule localized at adherens junctions which is widely expressed in various cell lines including neuronal, endothelial, epithelial and hematopoietic cells. Next to its role in adherens junctions it functions as alphaherpus virus receptor and acts also as intercellular adhesion molecule and pseudorabies virus receptor. Disruption of mouse nectin-2 leads to infertility of male mice. Monoclonal antibody 502-57 has been raised against the extracellular domain of mouse nectin-2. The antibody cross reacts with human nectin-2.
    Pathways
    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cell-Cell Junction Organization
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