TNFRSF10B Antikörper (Alexa Fluor 350)

Produktnummer ABIN2173760

Produktdetails anti-TNFRSF10B Antikörper (Alexa Fluor 350)

Target: TNFRSF10B (Tumor Necrosis Factor Receptor Superfamily, Member 10b (TNFRSF10B))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TNFRSF10B Antikörper ist konjugiert mit Alexa Fluor 350

Applikation: Western Blotting (WB)

Kreuzreaktivität: Human

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human DR5/CD262

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu TNFRSF10B

Target: TNFRSF10B (Tumor Necrosis Factor Receptor Superfamily, Member 10b (TNFRSF10B))

Andere Bezeichnung: Dr5 (TNFRSF10B Produkte)

Synonyme: TNFRSF10B antikoerper, dr5 antikoerper, cd262 antikoerper, killer antikoerper, trick2 antikoerper, trickb antikoerper, xDR-M1 antikoerper, xDR-M2 antikoerper, ztnfr9 antikoerper, trailr2 antikoerper, trick2a antikoerper, trick2b antikoerper, CD262 antikoerper, DR5 antikoerper, KILLER antikoerper, KILLER/DR5 antikoerper, TRAIL-R2 antikoerper, TRAILR2 antikoerper, TRICK2 antikoerper, TRICK2A antikoerper, TRICK2B antikoerper, TRICKB antikoerper, ZTNFR9 antikoerper, Ly98 antikoerper, MK antikoerper, tumor necrosis factor receptor superfamily, member 10b antikoerper, tumor necrosis factor receptor superfamily member 10b S homeolog antikoerper, tumor necrosis factor receptor superfamily member 10b L homeolog antikoerper, tumor necrosis factor receptor superfamily member 10b antikoerper, TNF receptor superfamily member 10b antikoerper, Tnfrsf10b antikoerper, TNFRSF10B antikoerper, tnfrsf10b.S antikoerper, tnfrsf10b.L antikoerper, tnfrsf10b antikoerper

Hintergrund:

Synonyms: Death receptor 5, CD 262, CD262, CD262 antigen, Death domain containing receptor for TRAIL/Apo2L, Death receptor 5, DR 5, DR5, Fas like protein precursor, KILLER, KILLER/DR5, p53 regulated DNA damage inducible cell death receptor (killer), TNF related apoptosis inducing ligand receptor 2, TNF-related apoptosis-inducing ligand receptor 2, TNFRSF10B, TRAIL R2, TRAIL receptor 2, TRAILR2, TRANCER, TRICK2, TRICK2A, TRICK2B, TRICKB, Tumor necrosis factor receptor like protein ZTNFR9, Tumor necrosis factor receptor superfamily member 10b, ZTNFR9.

Background: The protein encoded by this gene is a member of the TNF-receptor superfamily, and contains an intracellular death domain. This receptor can be activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL/APO-2L), and transduces an apoptosis signal. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein. Two transcript variants encoding different isoforms and one non-coding transcript have been found for this gene.

Pathways: p53 Signalweg, Apoptose, Positive Regulation of Endopeptidase Activity