SHC1 Antikörper (pSer36)

Produktnummer ABIN214820

Produktdetails anti-SHC1 Antikörper

Target: SHC1 (SHC (Src Homology 2 Domain Containing) Transforming Protein 1 (SHC1))

Bindungsspezifität: pSer36

Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Pferd, Schwein, Affe

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser SHC1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Spezifität: Recognizes human shc phosphorylated at Ser36. Species cross-reactivity: mouse and canine.

Aufreinigung: Gel filtration

Immunogen: Synthetic peptide corresponding to aa 33-39 (ELPpSPSA) of shc phosphorylated at Ser36. Molecular Weight: 66kD.

Type of Immunogen: Synthetic peptide

Klon: 6E10

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Approved: ELISA, WB (1 μg/mL)

Usage: Suitable for use in ELISA and Western Blot. Western Blot: 1 μg/mL for HRPO/ECL detection. Use Casein/Tween-20 based blocking and Blot incubation buffers. Positive control: S1010-92G1: Shc, phosphorylated (Ser36) HepG2 Cell Lysate, EGF Treated. Add 62 μL SDS-PAGE sample buffer and incubate at 90?C for 5 minutes. Aliquot and store at -20?C.

Kommentare:

Target Species of Antibody: Human

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: PBS,  pH 7.2, 0.1 % sodium azide, PEG, sucrose

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeat freeze-thaw cycles.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.

Details zu SHC1

Target: SHC1 (SHC (Src Homology 2 Domain Containing) Transforming Protein 1 (SHC1))

Andere Bezeichnung: p66 / SHC (SHC1 Produkte)

Synonyme: SHC1 antikoerper, SHC antikoerper, SHCA antikoerper, P66shc antikoerper, si:dkey-246i14.4 antikoerper, wu:fc10h03 antikoerper, shc antikoerper, p66shc antikoerper, Shc antikoerper, ShcA antikoerper, p66 antikoerper, SHC adaptor protein 1 antikoerper, Shc1p antikoerper, squalene--hopene cyclase antikoerper, SHC (Src homology 2 domain containing) transforming protein 1 antikoerper, SHC (Src homology 2 domain containing) transforming protein 1 L homeolog antikoerper, src homology 2 domain-containing transforming protein C1 antikoerper, SHC1 antikoerper, shc1 antikoerper, Shc1 antikoerper, shc1.L antikoerper

Hintergrund: Name/Gene ID: SHC1

Synonyms: SHC1, p46 shc, p52 shc, SH2 domain protein C1, p66, SHCA, SHC, SHC-transforming protein 1, SHC-transforming protein 3, SHC-transforming protein A

Molekulargewicht: 66kDa

Gen-ID: 6464

UniProt: P29353

Pathways: RTK Signalweg, T-Zell Rezeptor Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, ER-Nucleus Signaling, Signaling Events mediated by VEGFR1 and VEGFR2