Metabotropic Glutamate Receptor 5 Antikörper (N-Term)

Produktnummer ABIN213594

Produktdetails anti-Metabotropic Glutamate Receptor 5 Antikörper

Target: Metabotropic Glutamate Receptor 5 (GRM5) (Glutamate Receptor, Metabotropic 5 (GRM5))

Bindungsspezifität: N-Term

Reaktivität: Ratte, Human, Maus, Huhn, Hund, Affe, Schwein, Fledermaus, Rind (Kuh), Hamster, Pferd, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Metabotropic Glutamate Receptor 5 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Marke: IHC-plus™

Spezifität: Human GRM5 / MGLUR5. BLAST analysis of the peptide immunogen showed no homology with other human proteins.

Homologie: Percent identity with other species by BLAST analysis: Human, Gibbon, Monkey, Marmoset, Mouse, Rat, Dog, Bat, Bovine, Hamster, Horse, Rabbit, Pig, Turkey, Zebra finch, Chicken, Platypus, Lizard (100%) Xenopus (94%) Opossum, Pufferfish (88%) Zebrafish (82%).

Aufreinigung: Immunoaffinity purified

Immunogen: Synthetic 17 amino acid peptide from N-terminal extracellular domain of human GRM5 / MGLUR5. Percent identity with other species by BLAST analysis: Human, Gibbon, Monkey, Marmoset, Mouse, Rat, Dog, Bat, Bovine, Hamster, Horse, Rabbit, Pig, Turkey, Zebra finch, Chicken, Platypus, Lizard (100%), Xenopus (94%), Opossum, Pufferfish (88%), Zebrafish (82%).

Type of Immunogen: Synthetic peptide

Anwendungsinformationen

Applikationshinweise: Approved: IHC, IHC-P (5.6 μg/mL)

Usage: Immunohistochemistry: This antibody was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in  pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for this antibody was determined to be 5.6 μg/mL.

Kommentare:

Target Species of Antibody: Human

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: PBS, less than 0.1 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Aliquot and store undiluted at -20°C or below for up to 1 year. Can be stored undiluted at 4°C for up to 1 month. Avoid freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu Metabotropic Glutamate Receptor 5

Target: Metabotropic Glutamate Receptor 5 (GRM5) (Glutamate Receptor, Metabotropic 5 (GRM5))

Andere Bezeichnung: GRM5 / MGLUR5 (GRM5 Produkte)

Synonyme: GPRC1E antikoerper, MGLUR5 antikoerper, mGlu5 antikoerper, mGluR5 antikoerper, mGlur5 antikoerper, 6430542K11Rik antikoerper, AI850523 antikoerper, Glu5R antikoerper, Gprc1e antikoerper, mGluR5b antikoerper, glutamate receptor, metabotropic 5 antikoerper, glutamate metabotropic receptor 5 antikoerper, GRM5 antikoerper, Grm5 antikoerper

Hintergrund: Name/Gene ID: GRM5
Subfamily: Metabotropic glutamate
Family: GPCR

Synonyms: GRM5, GPRC1E, MGLUR5, Mglur5b, MGlu5

Gen-ID: 2915

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling, Regulation of long-term Neuronal Synaptic Plasticity