Metabotropic Glutamate Receptor 5 Produkte
(Glutamate Receptor, Metabotropic 5 (GRM5))
Kategorien
L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2009].
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Ausgewählte Metabotropic Glutamate Receptor 5 Kategorien
Metabotropic Glutamate Receptor 5 Antikörper
High quality antibodies with extensive validation data.
Metabotropic Glutamate Receptor 5 ELISA Kits
Reliable ELISA kits for a wide range of species.
Metabotropic Glutamate Receptor 5 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene Metabotropic Glutamate Receptor 5 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, IHC, ELISA, ICC, FACS, Neut
Validierungen
- (6)
Kat. Nr.
ABIN5611178
Menge
0.1 mg
Datenblatt
Datenblatt
Reaktivität
Human, Mouse, Rat
Applikation
WB, IHC, IF, ICC, LCI
Validierungen
- (5)
Kat. Nr.
ABIN7043250
Menge
25 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, PLA
Validierungen
- (3)
Kat. Nr.
ABIN516205
Menge
100 μg
Datenblatt
Datenblatt
Empfohlene Metabotropic Glutamate Receptor 5 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6967067
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Competition ELISA
Validierungen
Kat. Nr.
ABIN1743303
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Sheep
Analytical Method
Validierungen
Kat. Nr.
ABIN1774208
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene Metabotropic Glutamate Receptor 5 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1355782
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Insect Cells
Validierungen
- (1)
Kat. Nr.
ABIN3081171
Menge
1 mg
Datenblatt
Datenblatt
Reaktivität
Mouse
Source
Insect Cells
Validierungen
- (1)
Kat. Nr.
ABIN3122201
Menge
1 mg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren Metabotropic Glutamate Receptor 5 Produkten
: "Autism-associated Shank3 mutations alter mGluR expression and mGluR-dependent but not NMDA receptor-dependent long-term depression." in: Synapse (New York, N.Y.), Vol. 73, Issue 8, pp. e22097, (2019) (PubMed).: "Synaptic integration of newly generated neurons in rat dissociated hippocampal cultures." in: Molecular and cellular neurosciences, Vol. 47, Issue 3, pp. 203-14, (2011) (PubMed).
: "The clock gene Per2 influences the glutamatergic system and modulates alcohol consumption." in: Nature medicine, Vol. 11, Issue 1, pp. 35-42, (2005) (PubMed).
: "Group I metabotropic glutamate receptors mediate a dual role of glutamate in T cell activation." in: The Journal of biological chemistry, Vol. 279, Issue 32, pp. 33352-8, (2004) (PubMed).
: "Isoform-specific phosphorylation of metabotropic glutamate receptor 5 by protein kinase C (PKC) blocks Ca2+ oscillation and oscillatory translocation of Ca2+-dependent PKC." in: The Journal of biological chemistry, Vol. 279, Issue 3, pp. 2254-61, (2004) (PubMed).
: "Differential expression of mGluR5 in human lumbosacral motoneurons." in: Neuroreport, Vol. 15, Issue 2, pp. 271-3, (2004) (PubMed).
Synonyme und alternative Namen zu Metabotropic Glutamate Receptor 5
glutamate receptor, metabotropic 5 (GRM5), glutamate metabotropic receptor 5 (GRM5), glutamate metabotropic receptor 5 (Grm5), glutamate receptor, metabotropic 5 (Grm5), 6430542K11Rik, AI850523, Glu5R, GPRC1E, Gprc1e, mGlu5, MGLUR5, mGluR5, mGlur5, mGluR5bBezeichner auf Proteinebene für Metabotropic Glutamate Receptor 5
- metabotropic glutamate receptor 5
- metabotropic glutamate receptor 5 variant F
- metabotropic glutamate receptor 5 variant G
- metabotropic glutamate receptor 5 variant H
- metabotropic glutamate receptor (mGluR5)
- metabotropic glutamate receptor 5b
- G protein coupled receptor, family C, group 1, member E
- G protein-coupled receptor GRM5
- G protein-coupled receptor, family C, group 1, member E
- metabotropic glutamate receptor subtype 5b
- metabotropic glutamate receptor type 5
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