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Mesothelin Produkte

(Mesothelin (MSLN))

Kategorien

This gene encodes a precursor protein that is cleaved into two products, megakaryocyte potentiating factor and mesothelin. Megakaryocyte potentiation factor functions as a cytokine that can stimulate colony formation in bone marrow megakaryocytes. Mesothelian is a glycosylphosphatidylinositol-anchored cell-surface protein that may function as a cell adhesion protein. This protein is overexpressed in epithelial mesotheliomas, ovarian cancers and in specific squamous cell carcinomas. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Apr 2010].

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Ausgewählte Mesothelin Kategorien

Mesothelin Antikörper

High quality antibodies with extensive validation data.

Mesothelin ELISA Kits

Reliable ELISA kits for a wide range of species.

Mesothelin Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene Mesothelin Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation IHC (f)
Validierungen
  • (7)
Kat. Nr. ABIN6939032
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Applikation ELISA, WB, FACS, IHC (p)
Validierungen
  • (5)
Kat. Nr. ABIN727608
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation ELISA, FACS
Validierungen
  • (5)
Kat. Nr. ABIN6964068
Menge 100 μg
Datenblatt Datenblatt

Empfohlene Mesothelin ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Mouse
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
  • (1)
Kat. Nr. ABIN6957762
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
  • (1)
Kat. Nr. ABIN6957761
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6976025
Menge 96 tests
Datenblatt Datenblatt

Empfohlene Mesothelin Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Cynomolgus
Source HEK-293 Cells
Validierungen
  • (5)
Kat. Nr. ABIN7275282
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Source HEK-293 Cells
Validierungen
  • (5)
Kat. Nr. ABIN7275288
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Source HEK-293 Cells
Validierungen
  • (4)
Kat. Nr. ABIN7275283
Menge 100 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren Mesothelin Produkten

Li, Li, Xu, Xing, Ding, Jing, Wang, Hong: "Preclinical evaluation of a novel anti-mesothelin immunotoxin based on a single domain antibody as the targeting ligand." in: International journal of pharmaceutics, Vol. 602, pp. 120647, (2021) (PubMed).

Duong, Wu, Green, Bavaghar-Zaeimi, Wang, Labib, Zhou, Cantu, Jeganathan, Popescu, Pantea, de Perrot, Kelley: "A liquid biopsy for detecting circulating mesothelial precursor cells: A new biomarker for diagnosis and prognosis in mesothelioma." in: EBioMedicine, Vol. 61, pp. 103031, (2021) (PubMed).

Makita, Kunii, Sakurai, Ihara, Motohashi, Suzuki, Nakayama, Okamoto: "Activated iNKT cells enhance the anti-tumor effect of antigen specific CD8 T cells on mesothelin-expressing salivary gland cancer." in: BMC cancer, Vol. 18, Issue 1, pp. 1254, (2019) (PubMed).

Hung, Xu, Li, Ma, Jin, Viley, Allen, Natarajan, Shivakumar, Peshwa, Emens: "Development of Anti-Human Mesothelin-Targeted Chimeric Antigen Receptor Messenger RNA-Transfected Peripheral Blood Lymphocytes for Ovarian Cancer Therapy." in: Human gene therapy, Vol. 29, Issue 5, pp. 614-625, (2019) (PubMed).

Sirois, Deny, Li, Fall, Moore: "Engineered Fn3 protein has targeted therapeutic effect on mesothelin-expressing cancer cells and increases tumor cell sensitivity to chemotherapy." in: Biotechnology and bioengineering, (2019) (PubMed).

Zhang, Yang, Gu, Wu, Chi, Liu, Wang, Xue, Qi, Sun, Zhang, Hu, Xu: "Recombination of a dual-CAR-modified T lymphocyte to accurately eliminate pancreatic malignancy." in: Journal of hematology & oncology, Vol. 11, Issue 1, pp. 102, (2018) (PubMed).

Zhang, Khanna, Jiang, Alewine, Miettinen, Pastan, Hassan: "Efficacy of Anti-mesothelin Immunotoxin RG7787 plus Nab-Paclitaxel against Mesothelioma Patient-Derived Xenografts and Mesothelin as a Biomarker of Tumor Response." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 23, Issue 6, pp. 1564-1574, (2018) (PubMed).

Oehl, Kresoja-Rakic, Opitz, Vrugt, Weder, Stahel, Wild, Felley-Bosco: "Live-Cell Mesothelioma Biobank to Explore Mechanisms of Tumor Progression." in: Frontiers in oncology, Vol. 8, pp. 40, (2018) (PubMed).

Sirois, Deny, Baierl, George, Moore: "Fn3 proteins engineered to recognize tumor biomarker mesothelin internalize upon binding." in: PLoS ONE, Vol. 13, Issue 5, pp. e0197029, (2018) (PubMed).

Tang, Yang, Wang, Gu, Xia, Feng, Yang, Zhao, Su, Su, Wang: "Nucleoside reverse transcriptase inhibitor-induced rat oocyte dysfunction and low fertility mediated by autophagy." in: Oncotarget, Vol. 9, Issue 3, pp. 3895-3907, (2018) (PubMed).

Synonyme und alternative Namen zu Mesothelin

mesothelin (MSLN), mesothelin (Msln), mesothelin (LOC611363), mesothelin (LOC100524016), MPF, MSLN, SMRP

Bezeichner auf Proteinebene für Mesothelin

  • CAK1 antigen
  • megakaryocyte potentiating factor
  • pre-pro-megakaryocyte-potentiating factor
  • soluble MPF mesothelin related protein
  • ERC/mesothelin
  • protein expressed in renal carcinoma
  • mesothelin
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