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Menin Produkte

(Multiple Endocrine Neoplasia 1 (MEN1))

Kategorien

This gene encodes menin, a putative tumor suppressor associated with a syndrome known as multiple endocrine neoplasia type 1. In vitro studies have shown menin is localized to the nucleus, possesses two functional nuclear localization signals, and inhibits transcriptional activation by JunD, however, the function of this protein is not known. Two messages have been detected on northern blots but the larger message has not been characterized. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2008].

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Ausgewählte Menin Kategorien

Menin Antikörper

High quality antibodies with extensive validation data.

Menin ELISA Kits

Reliable ELISA kits for a wide range of species.

Menin Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene Menin Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation WB, ELISA, IHC, FACS
Validierungen
  • (5)
Kat. Nr. ABIN2682998
Menge 0.1 mg
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, IHC, IP, ICC
Validierungen
  • (4)
Kat. Nr. ABIN7443704
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human, Mouse, Rat
Applikation ELISA, IHC (p), IF (cc), IF (p), IHC (fro)
Validierungen
  • (4)
Kat. Nr. ABIN676343
Menge 100 μL
Datenblatt Datenblatt

Empfohlene Menin ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method
Validierungen
Kat. Nr. ABIN1142130
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Mouse
Analytical Method
Validierungen
Kat. Nr. ABIN1142131
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Rat
Analytical Method
Validierungen
Kat. Nr. ABIN1142132
Menge 96 tests
Datenblatt Datenblatt

Empfohlene Menin Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1310714
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1310718
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Mouse
Source Tobacco (Nicotiana tabacum)
Validierungen
  • (1)
Kat. Nr. ABIN3132147
Menge 1 mg
Datenblatt Datenblatt

Neueste Publikationen zu unseren Menin Produkten

Fang, Xia, Mahalingam, Virbasius, Wajapeyee, Green: "MEN1 is a melanoma tumor suppressor that preserves genomic integrity by stimulating transcription of genes that promote homologous recombination-directed DNA repair." in: Molecular and cellular biology, Vol. 33, Issue 13, pp. 2635-47, (2013) (PubMed).

Niu, Mei, Wang, Liu, Tian, Mo, Li, Lu, Xiao: "Phosphorylated olig1 localizes to the cytosol of oligodendrocytes and promotes membrane expansion and maturation." in: Glia, Vol. 60, Issue 9, pp. 1427-36, (2012) (PubMed).

Agarwal, Jothi: "Genome-wide characterization of menin-dependent H3K4me3 reveals a specific role for menin in the regulation of genes implicated in MEN1-like tumors." in: PLoS ONE, Vol. 7, Issue 5, pp. e37952, (2012) (PubMed).

Luzi, Marini, Giusti, Galli, Cavalli, Brandi: "The negative feedback-loop between the oncomir Mir-24-1 and menin modulates the Men1 tumorigenesis by mimicking the "Knudson's second hit"." in: PLoS ONE, Vol. 7, Issue 6, pp. e39767, (2012) (PubMed).

Veniaminova, Hayes, Varney, Merchant: "Conditional deletion of menin results in antral G cell hyperplasia and hypergastrinemia." in: American journal of physiology. Gastrointestinal and liver physiology, Vol. 303, Issue 6, pp. G752-64, (2012) (PubMed).

Xu, Wu, Wang, Shen, Guo, Shen, Wang: "Tumor suppressor menin mediates peripheral nerve injury-induced neuropathic pain through potentiating synaptic plasticity." in: Neuroscience, Vol. 223, pp. 473-85, (2012) (PubMed).

Wuescher, Angevine, Hinds, Ramakrishnan, Najjar, Mensah-Osman: "Insulin regulates menin expression, cytoplasmic localization, and interaction with FOXO1." in: American journal of physiology. Endocrinology and metabolism, Vol. 301, Issue 3, pp. E474-83, (2011) (PubMed).

Wu, Zhang, Huang, Yang, Hua: "Regulation of cyclin B2 expression and cell cycle G2/m transition by menin." in: The Journal of biological chemistry, Vol. 285, Issue 24, pp. 18291-300, (2010) (PubMed).

Shen, Ylaya, Pechhold, Wilson, Adem, Hewitt, Libutti: "Multiple endocrine neoplasia type 1 deletion in pancreatic alpha-cells leads to development of insulinomas in mice." in: Endocrinology, Vol. 151, Issue 8, pp. 4024-30, (2010) (PubMed).

Corbo, Dalai, Scardoni, Barbi, Beghelli, Bersani, Albarello, Doglioni, Schott, Capelli, Chilosi, Boninsegna, Becker, Falconi, Scarpa: "MEN1 in pancreatic endocrine tumors: analysis of gene and protein status in 169 sporadic neoplasms reveals alterations in the vast majority of cases." in: Endocrine-related cancer, Vol. 17, Issue 3, pp. 771-83, (2010) (PubMed).

Synonyme und alternative Namen zu Menin

menin 1 (MEN1), menin 1 (men1), menin 1 L homeolog (men1.L), multiple endocrine neoplasia I (men1), multiple endocrine neoplasia 1 (Men1), menin 1 (Men1), AW045611, MEAI, meai, menin, SCG2, scg2

Bezeichner auf Proteinebene für Menin

  • menin
  • multiple endocrine neoplasia protein
  • multiple endocrine neoplasia 1
  • multiple endocrine neoplasia I
  • menin-like
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