TLR6 Antikörper (N-Term)

Produktnummer ABIN1888182

Produktdetails anti-TLR6 Antikörper

Target: TLR6 (Toll-Like Receptor 6 (TLR6))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TLR6 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunocytochemistry (ICC)

Aufreinigung: Affinity chromatography purified via peptide column

Immunogen: Peptide corresponding to 15 amino acids near the amino terminus of human TLR6.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Handhabung: Avoid freezing and thawing repeatly.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Details zu TLR6

Target: TLR6 (Toll-Like Receptor 6 (TLR6))

Andere Bezeichnung: TLR6 (TLR6 Produkte)

Synonyme: TLR1 antikoerper, TLR16 antikoerper, CD286 antikoerper, TLR-6 antikoerper, toll-like receptor 1 family member A antikoerper, toll like receptor 6 antikoerper, toll-like receptor 6 antikoerper, TLR1A antikoerper, TLR6 antikoerper, Tlr6 antikoerper

Hintergrund: Toll-like receptors (TLRs) are evolutionarily conserved pattern-recognition molecules resembling the toll proteins that mediate antimicrobial responses in Drosophila.These proteins recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses.The TLRs act through adaptor molecules such as MyD88 and TIRAP to activate various kinases and transcription factors so the organism can respond to potential infection.TLR6 was first identified as a close homolog of TLR1, sharing 69% sequence identify.Like TLR1, TLR6 can form heterodimers with TLR2, and these TLR6:TLR2 dimers coordinate macrophage activation by Gram-positive bacteria and the yeast cell wall particle zymosan.Activation of these complexes not only initiates pro-inflammatory cascades, but also can lead to apoptotic responses.
Synonyms: Toll-like receptor 6

NCBI Accession: NP_006059

Pathways: TLR Signalweg, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades