CADPS Antikörper (N-Term)

Produktnummer ABIN1888141

Produktdetails anti-CADPS Antikörper

Target: CADPS (Ca++-Dependent Secretion Activator (CADPS))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CADPS Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Spezifität: Numerous isoforms of CAPS1 are known to exist.This CAPS1 antibody is predicted to be specific to CAPS1 and not recognize CAPS2.

Aufreinigung: Affinity chromatography purified via peptide column

Immunogen: 21 amino acid peptide near the amino terminus of the human CAPS1.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Handhabung: Avoid freezing and thawing repeatly.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Details zu CADPS

Target: CADPS (Ca++-Dependent Secretion Activator (CADPS))

Andere Bezeichnung: CAPS1 (CADPS Produkte)

Synonyme: CADPS1 antikoerper, CAPS antikoerper, CAPS1 antikoerper, Caps antikoerper, Caps1 antikoerper, Caps2 antikoerper, AU067781 antikoerper, mKIAA1121 antikoerper, CADPS antikoerper, cadps antikoerper, MGC122552 antikoerper, CAPS-1 antikoerper, caps antikoerper, caps1 antikoerper, si:busm1-1i3.1 antikoerper, si:busm1-6a2.7 antikoerper, si:dz6a2.7 antikoerper, calcium dependent secretion activator antikoerper, Ca2+-dependent secretion activator antikoerper, Ca2+-dependent activator protein for secretion b antikoerper, Ca2+ dependent secretion activator antikoerper, Ca2+ dependent secretion activator L homeolog antikoerper, Ca2+-dependent activator protein for secretion a antikoerper, CADPS antikoerper, Cadps antikoerper, cadpsb antikoerper, cadps antikoerper, cadps.L antikoerper, cadpsa antikoerper

Hintergrund: CAPS1 and its related protein CAPS2 encode novel neural/endocrine-specific cytosolic and peripheral membrane proteins.Both are essential components of the synaptic vesicle priming machinery and are required for the Ca2+-regulated exocytosis of secretory vesicles, CAPS-deficienct neurons contain no or very few fusion competent synaptic vesicles, causing a selective impairment of fast phasic transmitter release.CAPS1 acts at a stage in exocytosis that follows ATP-dependent priming, which involves the essential synthesis of phosphatidylinositol 4, 5-bisphosphate and is thought to be a specific regulator of large dense-core vesicle fusion.
Synonyms: Calcium-dependent secretion activator 1, CADPS1, CAPS?

NCBI Accession: NP_899631

Pathways: Synaptic Vesicle Exocytosis