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CADPS Antikörper (AA 151-250)

CADPS Reaktivität: Human IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN1385753
  • Target Alle CADPS Antikörper anzeigen
    CADPS (Ca++-Dependent Secretion Activator (CADPS))
    Bindungsspezifität
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 151-250
    Reaktivität
    • 13
    • 8
    • 8
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 13
    • 1
    Kaninchen
    Klonalität
    • 14
    Polyklonal
    Konjugat
    • 12
    • 1
    • 1
    Dieser CADPS Antikörper ist unkonjugiert
    Applikation
    • 11
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    Immunohistochemistry (Frozen Sections) (IHC (fro))
    Homologie
    Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human CAPS1
    Isotyp
    IgG
    Top Product
    Discover our top product CADPS Primärantikörper
  • Applikationshinweise
    IHC-F 1:100-500
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Haltbarkeit
    12 months
  • Target
    CADPS (Ca++-Dependent Secretion Activator (CADPS))
    Andere Bezeichnung
    CAPS1 (CADPS Produkte)
    Synonyme
    CADPS1 antikoerper, CAPS antikoerper, CAPS1 antikoerper, Caps antikoerper, Caps1 antikoerper, Caps2 antikoerper, AU067781 antikoerper, mKIAA1121 antikoerper, CADPS antikoerper, cadps antikoerper, MGC122552 antikoerper, CAPS-1 antikoerper, caps antikoerper, caps1 antikoerper, si:busm1-1i3.1 antikoerper, si:busm1-6a2.7 antikoerper, si:dz6a2.7 antikoerper, calcium dependent secretion activator antikoerper, Ca2+-dependent secretion activator antikoerper, Ca2+-dependent activator protein for secretion b antikoerper, Ca2+ dependent secretion activator antikoerper, Ca2+ dependent secretion activator L homeolog antikoerper, Ca2+-dependent activator protein for secretion a antikoerper, CADPS antikoerper, Cadps antikoerper, cadpsb antikoerper, cadps antikoerper, cadps.L antikoerper, cadpsa antikoerper
    Hintergrund

    Synonyms: Cadps, CADPS1, Calcium dependent secretion activator 1, Calcium-dependent activator protein for secretion 1, Calcium-dependent secretion activator 1, Caps, CAPS-1, rCAPS, CAPS1_HUMAN.

    Background: Calcium-dependent secretion activators (CAPS-1 and CAPS-2) are calcium-binding proteins that direct neurotransmitter and neuropeptide-filled vesicles to the cell membrane for secretory granule exocytosis. Both CAPS-1 and CAPS-2 are expressed primarily in the brain where they regulate the secretion of various substances. The CAPS proteins contain a PH domain that is essential for regulation of exocytosis, as well as regulation of phospholipid binding. Through their regulation of neurotrophin release from granule cells, CAPS proteins help to regulate cell fate during neuronal development. CAPS-1 is thought to regulate catecholamine release from neuronal cells, while CAPS-2 is thought to regulate release of both brain-derived neurotrophic factor (BDNF) and neurotrophin-3 (NT-3) from granule cells. Defects in the genes encoding CAPS-1 and CAPS-2 are implicated in impaired cerebral development and autism.

    Pathways
    Synaptic Vesicle Exocytosis
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