ATP11A Antikörper (N-Term)

Produktnummer ABIN1888107

Produktdetails anti-ATP11A Antikörper

Target: ATP11A (ATPase, Class VI, Type 11A (ATP11A))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ATP11A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunocytochemistry (ICC)

Aufreinigung: Affinity chromatography purified via peptide column

Immunogen: 19 amino acid peptide near the amino terminus of human ATP11A.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Handhabung: Avoid freezing and thawing repeatly.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Details zu ATP11A

Target: ATP11A (ATPase, Class VI, Type 11A (ATP11A))

Andere Bezeichnung: ATP11A (ATP11A Produkte)

Synonyme: ATPIH antikoerper, ATPIS antikoerper, 4930558F19Rik antikoerper, AU040868 antikoerper, Atpc1h antikoerper, Ih antikoerper, Ua20 antikoerper, si:dkey-251i8.1 antikoerper, ATPase phospholipid transporting 11A antikoerper, ATPase, class VI, type 11A antikoerper, ATP11A antikoerper, Atp11a antikoerper, atp11a antikoerper

Hintergrund: ATP11A is a widely expressed integral membrane ATPase.ATP11A is probably phosphorylated in its intermediate state and likely drives the transport of ions such as calcium or other molecules across membranes.While the exact molecule ATP11A transports is unknown, increased expression of ATP11A mRNA has been observed in murine leukemia cells made resistant to anti-cancer drugs such as farnesyltransferase inhibitors (FTIs).Furthermore, overexpression of ATP11A provided protection against the FTI SCH66336 while knockdown of ATP11A via siRNA made cells more sensitive to this drug.Other reports suggest that elevated levels of ATP11A mRNA may also be a predictive marker of metastasis in colorectal cancer patients.
Synonyms: ATPase class VI type 11A, ATPIH, ATPIS

NCBI Accession: NP_115565