ATP11A Antikörper (N-Term)

Produktnummer ABIN783659

Produktdetails anti-ATP11A Antikörper

Target: ATP11A (ATPase, Class VI, Type 11A (ATP11A))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ATP11A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)

Kreuzreaktivität (Details): Species reactivity (tested):Human, mouse, rat

Aufreinigung: Affinity chromatography purified via peptide column

Immunogen: 19 amino acid peptide near the amino terminus of human ATP11A

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Store the antibody (in aliquots) at -20 °C.

Details zu ATP11A

Target: ATP11A (ATPase, Class VI, Type 11A (ATP11A))

Andere Bezeichnung: ATP11A (ATP11A Produkte)

Synonyme: ATPIH antikoerper, ATPIS antikoerper, 4930558F19Rik antikoerper, AU040868 antikoerper, Atpc1h antikoerper, Ih antikoerper, Ua20 antikoerper, si:dkey-251i8.1 antikoerper, ATPase phospholipid transporting 11A antikoerper, ATPase, class VI, type 11A antikoerper, ATP11A antikoerper, Atp11a antikoerper, atp11a antikoerper

Hintergrund: ATP11A is a widely expressed integral membrane ATPase. ATP11A is probably phosphorylated in its intermediate state and likely drives the transport of ions such as calcium or other molecules across membranes. While the exact molecule ATP11A transports is unknown, increased expression of ATP11A mRNA has been observed in murine leukemia cells made resistant to anti-cancer drugs such as farnesyltransferase inhibitors (FTIs). Furthermore, overexpression of ATP11A provided protection against the FTI SCH66336 while knockdown of ATP11A via siRNA made cells more sensitive to this drug. Other reports suggest that elevated levels of ATP11A mRNA may also be a predictive marker of metastasis in colorectal cancer patients.Synonyms: ATPIH, ATPIS, ATPase IS, ATPase class VI type 11A, KIAA1021, Probable phospholipid-transporting ATPase IH

Gen-ID: 23250

NCBI Accession: NP_056020

UniProt: P98196