ATP11A Antikörper (N-Term)

Produktnummer ABIN6991379

Produktdetails anti-ATP11A Antikörper

Target: ATP11A (ATPase, Class VI, Type 11A (ATP11A))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ATP11A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)

Aufreinigung: ATP11A Antibody is affinity chromatography purified via peptide column.

Immunogen: ATP11A antibody was raised against a 19 amino acid synthetic peptide near the amino terminus of human ATP11A. The immunogen is located within the first 50 amino acids of ATP11A.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ATP11A antibody can be used for detection of ATP11A by Western blot at 1 μ,g/mL. Antibody can also be used for immunocytochemistry starting at 10 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunocytochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: ATP11A Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: ATP11A antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu ATP11A

Target: ATP11A (ATPase, Class VI, Type 11A (ATP11A))

Andere Bezeichnung: ATP11A (ATP11A Produkte)

Synonyme: ATPIH antikoerper, ATPIS antikoerper, 4930558F19Rik antikoerper, AU040868 antikoerper, Atpc1h antikoerper, Ih antikoerper, Ua20 antikoerper, si:dkey-251i8.1 antikoerper, ATPase phospholipid transporting 11A antikoerper, ATPase, class VI, type 11A antikoerper, ATP11A antikoerper, Atp11a antikoerper, atp11a antikoerper

Hintergrund: ATP11A Antibody: ATP11A is a widely expressed integral membrane ATPase. ATP11A is probably phosphorylated in its intermediate state and likely drives the transport of ions such as calcium or other molecules across membranes. While the exact molecule ATP11A transports is unknown, increased expression of ATP11A mRNA has been observed in murine leukemia cells made resistant to anti-cancer drugs such as farnesyltransferase inhibitors (FTIs). Furthermore, overexpression of ATP11A provided protection against the FTI SCH66336 while knockdown of ATP11A via siRNA made cells more sensitive to this drug. Other reports suggest that elevated levels of ATP11A mRNA may also be a predictive marker of metastasis in colorectal cancer patients.

Gen-ID: 23250

NCBI Accession: NP_115565

UniProt: P98196