RHEB Antikörper (Middle Region)

Produktnummer ABIN1887803

Produktdetails anti-RHEB Antikörper

Target: RHEB (Ras Homolog Enriched in Brain (RHEB))

Bindungsspezifität: Middle Region

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RHEB Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Aufreinigung: Affinity chromatography purified via peptide column

Immunogen: 15 amino acid peptide from the middle region of human Rheb.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Handhabung: Avoid freezing and thawing repeatly.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Details zu RHEB

Target: RHEB (Ras Homolog Enriched in Brain (RHEB))

Andere Bezeichnung: Rheb (RHEB Produkte)

Synonyme: RHEB2 antikoerper, RHEB antikoerper, rheb2 antikoerper, CG1081 antikoerper, DReb antikoerper, Dm Rheb antikoerper, DmRheb antikoerper, Dmel\CG1081 antikoerper, Q9VND8 antikoerper, RheB antikoerper, dRheb antikoerper, rheb antikoerper, Ras homolog, mTORC1 binding antikoerper, Ras homolog enriched in brain antikoerper, ras homolog enriched in brain antikoerper, Ras homolog, mTORC1 binding L homeolog antikoerper, RHEB antikoerper, Rheb antikoerper, rheb antikoerper, rheb.L antikoerper

Hintergrund: Rheb (Ras homolog enriched in brain) is an evolutionarily conserved member of the Ras family of small GTP-binding proteins originally found to be rapidly induced by synaptic activity in the hippocampus following seizure.While it is expressed at relatively high levels in the brain, Rheb is widely expressed in other tissues and may be induced by growth factor stimulation.Similar to other family members, Rheb triggers activation of the Raf-MEK-MAPK pathway.Biochemical and genetic studies demonstrate that Rheb has an important role in regulating the insulin/Target of rapamycin (TOR) signaling pathway.TOR is a serine/threonine protein kinase that acts as a sensor for ATP and amino acids, balancing the availability of nutrients with protein translation and cell growth.A dimeric protein complex termed TSC1/TSC2 indirectly inhibits TOR activity by inhibiting Rheb via the GAP activity of TSC2.

Pathways: RTK Signalweg