RHEB Produkte
(Ras Homolog Enriched in Brain (RHEB))
Kategorien
This gene is a member of the small GTPase superfamily and encodes a lipid-anchored, cell membrane protein with five repeats of the RAS-related GTP-binding region. This protein is vital in regulation of growth and cell cycle progression due to its role in the insulin/TOR/S6K signaling pathway. The protein has GTPase activity and shuttles between a GDP-bound form and a GTP-bound form, and farnesylation of the protein is required for this activity. Three pseudogenes have been mapped, two on chromosome 10 and one on chromosome 22. [provided by RefSeq, Jul 2008].
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Ausgewählte RHEB Kategorien
RHEB Antikörper
High quality antibodies with extensive validation data.
RHEB Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene RHEB Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA
Validierungen
- (1)
- (6)
Kat. Nr.
ABIN519784
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
ELISA, IHC
Validierungen
- (2)
Kat. Nr.
ABIN7154592
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Mouse, Rat
Applikation
WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro)
Validierungen
- (2)
Kat. Nr.
ABIN704771
Menge
100 μL
Datenblatt
Datenblatt
Empfohlene RHEB ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
Kat. Nr.
ABIN6951226
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene RHEB Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
- (1)
Kat. Nr.
ABIN7124780
Menge
50 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
- (1)
Kat. Nr.
ABIN666866
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1317998
Menge
10 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren RHEB Produkten
: "RHEB: a potential regulator of chondrocyte phenotype for cartilage tissue regeneration." in: Journal of tissue engineering and regenerative medicine, (2016) (PubMed).: "In vivo AAV1 transduction with hRheb(S16H) protects hippocampal neurons by BDNF production." in: Molecular therapy : the journal of the American Society of Gene Therapy, Vol. 23, Issue 3, pp. 445-55, (2015) (PubMed).
: "Spatial control of the TSC complex integrates insulin and nutrient regulation of mTORC1 at the lysosome." in: Cell, Vol. 156, Issue 4, pp. 771-85, (2014) (PubMed).
: "Formation of endothelial lumens requires a coordinated PKCepsilon-, Src-, Pak- and Raf-kinase-dependent signaling cascade downstream of Cdc42 activation." in: Journal of cell science, Vol. 122, Issue Pt 11, pp. 1812-22, (2009) (PubMed).
: "Phospholipase D1 is an effector of Rheb in the mTOR pathway." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 105, Issue 24, pp. 8286-91, (2008) (PubMed).
: "Rheb activates mTOR by antagonizing its endogenous inhibitor, FKBP38." in: Science (New York, N.Y.), Vol. 318, Issue 5852, pp. 977-80, (2007) (PubMed).
: "Rheb GTPase is a direct target of TSC2 GAP activity and regulates mTOR signaling." in: Genes & development, Vol. 17, Issue 15, pp. 1829-34, (2003) (PubMed).
: "Rheb is an essential regulator of S6K in controlling cell growth in Drosophila." in: Nature cell biology, Vol. 5, Issue 6, pp. 559-65, (2003) (PubMed).
: "Rheb is a direct target of the tuberous sclerosis tumour suppressor proteins." in: Nature cell biology, Vol. 5, Issue 6, pp. 578-81, (2003) (PubMed).
: "Rheb interacts with Raf-1 kinase and may function to integrate growth factor- and protein kinase A-dependent signals." in: Molecular and cellular biology, Vol. 17, Issue 2, pp. 921-33, (1997) (PubMed).
Synonyme und alternative Namen zu RHEB
Ras homolog, mTORC1 binding (RHEB), Ras homolog enriched in brain (Rheb), Ras homolog, mTORC1 binding (Rheb), Ras homolog enriched in brain (RHEB), Ras homolog, mTORC1 binding (rheb), ras homolog enriched in brain (rheb), Ras homolog, mTORC1 binding L homeolog (rheb.L), CG1081, Dmel\CG1081, Dm Rheb, DmRheb, DReb, dRheb, Q9VND8, RHEB, RheB, rheb, RHEB2, rheb2Bezeichner auf Proteinebene für RHEB
- GTP-binding protein Rheb
- Ras homolog enriched in brain 2
- RAS-homolog enriched in brain
- Ras homolog enriched in brain
- ras homolog enriched in brain
- GTP-binding protein rheb
- CG1081 gene product from transcript CG1081-RA
- CG1081-PA
- CG1081-PB
- RAS homolog enriched in brain
- Ras homolog enriched in brain ortholog
- Ras homologue enriched in brain
- Ras homology enriched in brain
- Rheb-PA
- Rheb-PB
- Ras homolog enriched in brain L homeolog
- Ras homolog, mTORC1 binding L homeolog
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