NLRC3 Antikörper (Center)

Produktnummer ABIN1887754

Produktdetails anti-NLRC3 Antikörper

Target: NLRC3 (NLR Family, CARD Domain Containing 3 (NLRC3))

Bindungsspezifität: Center

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NLRC3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Aufreinigung: Affinity chromatography purified via peptide column

Immunogen: NOD3 antibody was raised against an 18 amino acid peptide near the center of human NOD3.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Handhabung: Avoid freezing and thawing repeatly.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Details zu NLRC3

Target: NLRC3 (NLR Family, CARD Domain Containing 3 (NLRC3))

Andere Bezeichnung: NOD3 (NLRC3 Produkte)

Synonyme: NLRC3 antikoerper, nod3 antikoerper, NLR-A3 antikoerper, NOD3 antikoerper, CLR16.2 antikoerper, D230007K08Rik antikoerper, mFLJ00348 antikoerper, Nlrc3-ps1 antikoerper, RGD1304902 antikoerper, NLR family CARD domain containing 3 antikoerper, NLR family, CARD domain containing 3 antikoerper, NLRC3 antikoerper, nlrc3 antikoerper, Nlrc3 antikoerper

Hintergrund: NOD3 is a member of the NOD (nucleotide-binding oligomerization domain) family, a group of proteins that are involved in innate immune defense.NOD3 also known as NLR family CARD containing 3 (NLRC3), is predominantly expressed in the immune system, particularly in T lymphocytes, and its expression is strongly down-regulated following stimulation of the T-cell receptor complex and CD28, suggesting that NOD3 plays a role in attenuating the activation of T cells.NOD3 inhibits NF-kappaB, AP-1 and NFAT transcriptional activation in Jurkat T cells downstream of CD3/CD28 stimulation or treatment with PMA/ionomycin and decreases IL-2 and CD25 mRNA induction in activated cells.
Synonyms: Nucleotide-binding oligomerization domain containing 3, NLRC3, CLR16.2