CDIP1 Antikörper (Center)

Produktnummer ABIN1887614

Produktdetails anti-CDIP1 Antikörper

Target: CDIP1 (LITAF-Like Protein (CDIP1))

Bindungsspezifität: Center

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CDIP1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Aufreinigung: Affinity chromatography purified via peptide column

Immunogen: 16 amino acid peptide near the center of human CDIP.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Handhabung: Avoid freezing and thawing repeatly.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Details zu CDIP1

Target: CDIP1 (LITAF-Like Protein (CDIP1))

Andere Bezeichnung: CDIP (CDIP1 Produkte)

Synonyme: RGD1310686 antikoerper, MGC165666 antikoerper, MGC97537 antikoerper, 2700048O17Rik antikoerper, 5730403B10Rik antikoerper, AU018521 antikoerper, AW742692 antikoerper, CDIP antikoerper, C16orf5 antikoerper, I1 antikoerper, LITAFL antikoerper, MGC52765 antikoerper, MGC127651 antikoerper, cell death-inducing p53 target 1 antikoerper, LITAF-like protein antikoerper, cell death inducing Trp53 target 1 antikoerper, cell death inducing p53 target 1 antikoerper, cell death-inducing p53 target 1 L homeolog antikoerper, Cdip1 antikoerper, cdip1 antikoerper, Bm1_00175 antikoerper, LOC100168843 antikoerper, CDIP1 antikoerper, cdip1.L antikoerper

Hintergrund: The p53 tumor-suppressor gene integrates numerous signals that control cell life and death, loss of its functions contributes to the development of most cancers.CDIP is a novel pro-apoptotic target gene whose inhibition abrogates p53-mediated apoptotic responses.Overexpression of CDIP induced apoptosis in transfected cells while siRNA suppression of caspase-8 mRNA blocked this CDIP-induced apoptosis, indicating that the CDIP-dependent apoptosis pathway proceeds through extrinsic cell death pathway.CDIP may thus represent a novel target for drug design to maximize p53 response and sensitize tumor cells to cancer therapy.Multiple isoforms of CDIP are known to exist.
Synonyms: Cell death involved p53-target

NCBI Accession: NP_037531