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CDIP1 Antikörper (AA 70-120)

CDIP1 Reaktivität: Human, Maus WB, ELISA, IF, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6991072
  • Target Alle CDIP1 Antikörper anzeigen
    CDIP1 (LITAF-Like Protein (CDIP1))
    Bindungsspezifität
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 70-120
    Reaktivität
    • 6
    • 4
    • 1
    Human, Maus
    Wirt
    • 5
    • 2
    Kaninchen
    Klonalität
    • 7
    Polyklonal
    Konjugat
    • 7
    Dieser CDIP1 Antikörper ist unkonjugiert
    Applikation
    • 7
    • 2
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Aufreinigung
    CDIP Antibody is affinity chromatography purified via peptide column.
    Immunogen
    CDIP antibody was raised against a 19 amino acid synthetic peptide near the center of human CDIP. The immunogen is located within amino acids 70 - 120 of CDIP.
    Isotyp
    IgG
    Top Product
    Discover our top product CDIP1 Primärantikörper
  • Applikationshinweise
    CDIP antibody can be used for detection of CDIP by Western blot at 0.25 - 0.5 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

    Antibody validated: Western Blot in human samples, Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    CDIP Antibody is supplied in PBS containing 0.02 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C,4 °C
    Informationen zur Lagerung
    CDIP antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • Target
    CDIP1 (LITAF-Like Protein (CDIP1))
    Andere Bezeichnung
    CDIP (CDIP1 Produkte)
    Synonyme
    RGD1310686 antikoerper, MGC165666 antikoerper, MGC97537 antikoerper, 2700048O17Rik antikoerper, 5730403B10Rik antikoerper, AU018521 antikoerper, AW742692 antikoerper, CDIP antikoerper, C16orf5 antikoerper, I1 antikoerper, LITAFL antikoerper, MGC52765 antikoerper, MGC127651 antikoerper, cell death-inducing p53 target 1 antikoerper, LITAF-like protein antikoerper, cell death inducing Trp53 target 1 antikoerper, cell death inducing p53 target 1 antikoerper, cell death-inducing p53 target 1 L homeolog antikoerper, Cdip1 antikoerper, cdip1 antikoerper, Bm1_00175 antikoerper, LOC100168843 antikoerper, CDIP1 antikoerper, cdip1.L antikoerper
    Hintergrund
    CDIP Antibody: The p53 tumor-suppressor gene integrates numerous signals that control cell life and death, loss of its functions contributes to the development of most cancers. CDIP is a novel pro-apoptotic target gene whose inhibition abrogates p53-mediated apoptotic responses. Overexpression of CDIP induced apoptosis in transfected cells while siRNA suppression of caspase-8 mRNA blocked this CDIP-induced apoptosis, indicating that the CDIP-dependent apoptosis pathway proceeds through extrinsic cell death pathway. CDIP may thus represent a novel target for drug design to maximize p53 response and sensitize tumor cells to cancer therapy. Multiple isoforms of CDIP are known to exist.
    Gen-ID
    29965
    NCBI Accession
    NP_037531
    UniProt
    Q9H305
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