LY86 Antikörper (Center)

Produktnummer ABIN1887548

Produktdetails anti-LY86 Antikörper

Target: LY86 (Lymphocyte Antigen 86 (LY86))

Bindungsspezifität: Center

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser LY86 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Aufreinigung: Affinity chromatography purified via peptide column

Immunogen: 15 amino acid peptide from near the center of human MD-1.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Handhabung: Avoid freezing and thawing repeatly.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Details zu LY86

Target: LY86 (Lymphocyte Antigen 86 (LY86))

Andere Bezeichnung: MD-1 (LY86 Produkte)

Synonyme: MD-1 antikoerper, MMD-1 antikoerper, dJ80N2.1 antikoerper, MD1 antikoerper, LY86 antikoerper, lymphocyte antigen 86 antikoerper, LY86 antikoerper, Ly86 antikoerper

Hintergrund: Toll-like receptors (TLRs) are evolutionarily conserved pattern-recognition molecules that recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses.The signaling of these TLRs is kept under tight control by the expression of endogenous inhibiting proteins such as RP105, a recently identified homolog of TLR4.This protein, in association with MD-1, interacts with and inhibits the TLR4/MD-2 signaling pathway.While MD-2 can directly bind to LPS, one of the activating molecules of TLR4, the function of MD-1 is less well-known.It has been suggested however, that the RP105/MD-1 complex influences antibody production mediated by both TLR4/MD-2 and TLR2 receptor complexes.
Synonyms: Lymphocyte antigen 86

NCBI Accession: NP_004262

Pathways: Toll-Like Receptors Cascades