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LY86 Antikörper (Lymphocyte Antigen 86) Primary Antibody

LY86 Reaktivität: Maus Func, FACS Wirt: Ratte Monoclonal MD113 unconjugated
Pubmed (1 reference)
Produktnummer ABIN2191781
$547.49
Zzgl. Versandkosten $45.00
100 μg
Lieferung in 6 bis 8 Werktagen
  • Target Alle LY86 Antikörper anzeigen
    LY86
    Reaktivität
    • 42
    • 27
    • 22
    Maus
    Wirt
    • 52
    • 8
    • 5
    Ratte
    Klonalität
    • 55
    • 10
    Monoklonal
    Konjugat
    • 29
    • 7
    • 6
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser LY86 Antikörper ist unkonjugiert
    Applikation
    • 39
    • 22
    • 13
    • 13
    • 11
    • 11
    • 9
    • 5
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    Functional Studies (Func), Flow Cytometry (FACS)
    Sterilität
    0.2 μm filtered
    Klon
    MD113
  • Applikationshinweise
    For flow cytometry, dilutions to be used depend on detection system applied. It is recommended that users test the reagent and determine their own optimal dilutions. The typical starting working dilution is 1:50. Before use in biological assays, the product must be filter sterilized and depending on the concentration to be used dialyzed against culture medium to remove the sodium azide added. Please inquire for availability of azide free solutions.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Buffer
    PBS, containing 0.1 % bovine serum albumin and 0.02 % sodium azide.
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C
    Informationen zur Lagerung
    Product should be stored at 4 °C. Under recommended storage conditions, product is stable for one year.
    Haltbarkeit
    12 months
  • Nagai, Shimazu, Ogata, Akashi, Sudo, Yamasaki, Hayashi, Iwakura, Kimoto, Miyake: "Requirement for MD-1 in cell surface expression of RP105/CD180 and B-cell responsiveness to lipopolysaccharide." in: Blood, Vol. 99, Issue 5, pp. 1699-705, (2002) (PubMed).

  • Target
    LY86
    Andere Bezeichnung
    Md-1 (LY86 Produkte)
    Synonyme
    MD-1, MMD-1, dJ80N2.1, MD1, LY86, lymphocyte antigen 86, LY86, Ly86
    Hintergrund
    The monoclonal antibody MD113 reacts with mouse MD-1. MD-1 (22-25 kD) is an extracellular protein associated with the extracellular domain of RP105. The latter is a type 1 transmembrane protein with leucine-rich repeats. RP105 is similar to Drosophila Toll. MD-1 associated with RP105 (similar to TLR4/MD-2) appears to be an essential molecule that helps RP105 on B-cells to signal to LPS. The MD113 antibody is antagonistic in LPS-induced B-cell proliferation and B7.2 up-regulation.
    Pathways
    Toll-Like Receptors Cascades
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