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LY86 Antikörper (C-Term)

LY86 Reaktivität: Human EIA, IHC (p), WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN500258
$646.80
Zzgl. Versandkosten $45.00
0.1 mg
Available
  • Target Alle LY86 Antikörper anzeigen
    LY86 (Lymphocyte Antigen 86 (LY86))
    Bindungsspezifität
    • 15
    • 9
    • 8
    • 8
    • 7
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reaktivität
    • 40
    • 28
    • 22
    Human
    Wirt
    • 51
    • 9
    • 4
    Kaninchen
    Klonalität
    • 53
    • 11
    Polyklonal
    Konjugat
    • 28
    • 7
    • 6
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser LY86 Antikörper ist unkonjugiert
    Applikation
    • 37
    • 22
    • 13
    • 13
    • 12
    • 9
    • 9
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 1
    Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
    Spezifität
    This antibody detects MD-1 at C-term.
    Kreuzreaktivität (Details)
    Species reactivity (tested):Human
    Aufreinigung
    Peptide affinity chromatography
    Immunogen
    MD-1 antibody was raised against a 14 amino acid peptide from near the carboxy terminus of human MD-1.
    Isotyp
    IgG
  • Applikationshinweise
    ELISA. Western blot: 0.5 - 1 μg/mL. Immunohistochemistry on paraffin sections.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Buffer
    PBS containing 0.02 % sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
  • Target
    LY86 (Lymphocyte Antigen 86 (LY86))
    Andere Bezeichnung
    LY86 / MD-1 (LY86 Produkte)
    Synonyme
    MD-1, MMD-1, dJ80N2.1, MD1, LY86, lymphocyte antigen 86, LY86, Ly86
    Hintergrund
    Toll-like receptors (TLRs) are evolutionarily conserved pattern-recognition molecules that recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses. The signaling of these TLRs is kept under tight control by the expression of endogenous inhibiting proteins such as RP105, a recently identified homolog of TLR4. This protein, in association with MD-1, interacts with and inhibits the TLR4/MD-2 signaling pathway.. While MD-2 can directly bind to LPS, one of the activating molecules of TLR4, the function of MD-1 is less well-known. It has been suggested however, that the RP105/MD-1 complex influences antibody production mediated by both TLR4/MD-2 and TLR2 receptor complexes.Synonyms: Lymphocyte antigen 86, MD1
    Gen-ID
    9450
    NCBI Accession
    NP_004262
    UniProt
    O95711
    Pathways
    Toll-Like Receptors Cascades
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