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AGT Antikörper (AA 1-446)
AGT
Reaktivität: Human
WB, IHC, IF
Wirt: Kaninchen
Polyclonal
unconjugated
Produktnummer ABIN1885927
Produktdetails anti-AGT Antikörper
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Target
Alle AGT Antikörper anzeigen
AGT
(Angiotensinogen (serpin Peptidase Inhibitor, Clade A, Member 8) (AGT))
Bindungsspezifität
Alle Epitope für AGT Antikörper
AA 1-446
Reaktivität
Alle Reaktivitäten für AGT Antikörper
Human
Wirt
Alle Wirte für AGT Antikörper
Kaninchen
Klonalität
Alle Klonalitäten für AGT Antikörper
Polyklonal
Konjugat
Alle Konjugate für AGT Antikörper
Dieser AGT Antikörper ist unkonjugiert
Applikation
Alle Applikationen für AGT Antikörper
Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
Aufreinigung
Purified by antigen-affinity chromatography.
Immunogen
Recombinant protein fragment contain a sequence corresponding to a region within amino acids 1 and 446 of Human AGT
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Alternativen
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Anwendungsinformationen
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Applikationshinweise
Suggested dilutions: Western blotting: 1.500-1.3000 Immunohistochemistry: 1.100-1.250 Immunofluorescence: 1.100-1.200
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
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Format
Liquid
Buffer
0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.
Konservierungsmittel
Thimerosal (Merthiolate)
Vorsichtsmaßnahmen
Biohazard Informations: This product contains thimerosal which is hazardous.
Lagerung
4 °C/-20 °C
Informationen zur Lagerung
Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
Details zu AGT
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Target
AGT
(Angiotensinogen (serpin Peptidase Inhibitor, Clade A, Member 8) (AGT))
Abstract
AGT Produkte
Synonyme
ANHU antikoerper, SERPINA8 antikoerper, AI265500 antikoerper, AngI antikoerper, AngII antikoerper, Aogen antikoerper, Serpina8 antikoerper, ANRT antikoerper, Ang antikoerper, PAT antikoerper, wu:fb62f06 antikoerper, wu:fj87b02 antikoerper, zgc:111892 antikoerper, AGT antikoerper, angt antikoerper, ANGT antikoerper, angiotensinogen antikoerper, angiotensinogen (serpin peptidase inhibitor, clade A, member 8) antikoerper, AGT antikoerper, Agt antikoerper, agt antikoerper
Hintergrund
The protein encoded by this gene, pre-angiotensinogen or angiotensinogen precursor, is expressed in the liver and is cleaved by the enzyme renin in response to lowered blood pressure.The resulting product, angiotensin I, is then cleaved by angiotensin converting enzyme (ACE) to generate the physiologically active enzyme angiotensin II.The protein is involved in maintaining blood pressure and in the pathogenesis of essential hypertension and preeclampsia.Mutations in this gene are associated with susceptibility to essential hypertension, and can cause renal tubular dysgenesis, a severe disorder of renal tubular development.Defects in this gene have also been associated with non-familial structural atrial fibrillation, and inflammatory bowel disease.[provided by RefSeq] Synonyms: ANHU, FLJ92595, FLJ97926, SERPINA8
Molekulargewicht
53 kDa
Gen-ID
183
NCBI Accession
NM_000029 , NP_000020
Pathways
JAK-STAT Signalweg , ACE Inhibitor Pathway , EGFR Signaling Pathway , Peptide Hormone Metabolism , Regulation of Systemic Arterial Blood Pressure by Hormones , Regulation of Lipid Metabolism by PPARalpha , Protein targeting to Nucleus , Feeding Behaviour , Monocarboxylic Acid Catabolic Process , Dicarboxylic Acid Transport , Positive Regulation of Response to DNA Damage Stimulus , Regulation of long-term Neuronal Synaptic Plasticity
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