LY96 Antikörper (AA 2-160)

Produktnummer ABIN1885505

Produktdetails anti-LY96 Antikörper

Target: LY96 (Lymphocyte Antigen 96 (LY96))

Bindungsspezifität: AA 2-160

Reaktivität: Human, Maus, Ratte

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser LY96 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Aufreinigung: Immunoaffinity chromotography purified IgG

Immunogen: Raised against a recombinant protein corresponding to amino acids 2 to 160 of human MD-2

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Lagerung: -20 °C

Informationen zur Lagerung: Can be stored at -20 °C, stable for one year.

Haltbarkeit: 12 months

Details zu LY96

Target: LY96 (Lymphocyte Antigen 96 (LY96))

Andere Bezeichnung: MD-2 (LY96 Produkte)

Synonyme: MD2 antikoerper, ESOP-1 antikoerper, MD-2 antikoerper, ly-96 antikoerper, Ly-96 antikoerper, Md2 antikoerper, lymphocyte antigen 96 antikoerper, LY96 antikoerper, Ly96 antikoerper

Hintergrund: MD-2 is a member of the Toll/interleukin-1 receptor (TIR) family, a group of proteins that include the Toll-like receptors (TLRs).TLRs are signaling molecules that recognize different pathogen-associated molecular patterns (PAMPs) and serve as an important link between the innate and adaptive immune responses.TLR4, the major signaling receptor for lipopolysaccharide (LPS), requires the binding of MD-2 to its extracellular region for maximal response to LPS.Theof this response is determined by the species of MD-2, e.g., human MD-2 transfected into mouse cells can cause mouse TLR4 to react to LPS analogs that are normally antagonistic to human but not mouse TLR4.
Synonyms: MD-2 (1A2E3).Lymphocyte antigen 96 precursor, ESOP-1

NCBI Accession: NP_056179

Pathways: TLR Signalweg, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades