PARP3 Antikörper (N-Term)

Produktnummer ABIN1881632

Produktdetails anti-PARP3 Antikörper

Target: PARP3 (Poly (ADP-Ribose) Polymerase Family, Member 3 (PARP3))

Bindungsspezifität: AA 99-126, N-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PARP3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This PARP3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 99-126 amino acids from the N-terminal region of human PARP3.

Klon: RB42819

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Haltbarkeit: 6 months

Details zu PARP3

Target: PARP3 (Poly (ADP-Ribose) Polymerase Family, Member 3 (PARP3))

Andere Bezeichnung: PARP3 (PARP3 Produkte)

Synonyme: ADPRT-3 antikoerper, PARP-3 antikoerper, PM38 antikoerper, Adprtl3 antikoerper, fj17c06 antikoerper, wu:fj17c06 antikoerper, zgc:66157 antikoerper, PARP3 antikoerper, parp3 antikoerper, ADPRT3 antikoerper, ADPRTL2 antikoerper, ADPRTL3 antikoerper, ARTD3 antikoerper, IRT1 antikoerper, PADPRT-3 antikoerper, A930002C11Rik antikoerper, AW990611 antikoerper, Adprt3 antikoerper, pADPRT-3 antikoerper, seed maturation protein PM38 antikoerper, poly (ADP-ribose) polymerase family, member 3 antikoerper, poly(ADP-ribose) polymerase family member 3 antikoerper, poly(ADP-ribose) polymerase family member 3 L homeolog antikoerper, PARP3 antikoerper, parp3 antikoerper, parp3.L antikoerper, Parp3 antikoerper

Hintergrund: Involved in the base excision repair (BER) pathway, by catalyzing the poly(ADP-ribosyl)ation of a limited number of acceptor proteins involved in chromatin architecture and in DNA metabolism. This modification follows DNA damages and appears as an obligatory step in a detection/signaling pathway leading to the reparation of DNA strand breaks. May link the DNA damage surveillance network to the mitotic fidelity checkpoint. Negatively influences the G1/S cell cycle progression without interfering with centrosome duplication. Binds DNA. May be involved in the regulation of PRC2 and PRC3 complex-dependent gene silencing.

Molekulargewicht: 60089

NCBI Accession: NP_001003931, NP_005476

UniProt: Q9Y6F1