PARP3 Antikörper (C-Term)

Produktnummer ABIN2778113

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch PARP3 in IHC und WB. Es zeigt Reaktivität gegenüber Proben von Human, Maus, Ratte, Pferd, Kaninchen, Rind (Kuh), Hund und Schwein.Es wurde in 1 Publikation zitiert.

Kurzübersicht für PARP3 Antikörper (C-Term) (ABIN2778113)

Target: PARP3 (Poly (ADP-Ribose) Polymerase Family, Member 3 (PARP3))

Reaktivität: Human, Maus, Ratte, Pferd, Kaninchen, Rind (Kuh), Hund, Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PARP3 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), Western Blotting (WB)

Produktdetails anti-PARP3 Antikörper

Bindungsspezifität: C-Term

Verwendungszweck: PARP3 Antibody - C-terminal region

Sequenz: LGREHHINTD NPSLKSPPPG FDSVIARGHT EPDPTQDTEL ELDGQQVVVP

Homologie: Cow: 92%, Dog: 91%, Horse: 100%, Human: 100%, Mouse: 77%, Pig: 85%, Rabbit: 100%, Rat: 92%

Produktmerkmale: This is a rabbit polyclonal antibody against PARP3. It was validated on Western Blot and immunohistochemistry.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human PARP3

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8108441

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-PARP3 Antikörper (ABIN2778113)

Augustin, Spenlehauer, Dumond, Ménissier-De Murcia, Piel, Schmit, Apiou, Vonesch, Kock, Bornens, De Murcia: "PARP-3 localizes preferentially to the daughter centriole and interferes with the G1/S cell cycle progression." in: Journal of cell science, Vol. 116, Issue Pt 8, pp. 1551-62, (2003) (PubMed).

Details zu PARP3

Target: PARP3 (Poly (ADP-Ribose) Polymerase Family, Member 3 (PARP3))

Andere Bezeichnung: PARP3

Hintergrund:

Background Information: The protein encoded by this gene belongs to the PARP family. These enzymes modify nuclear proteins by poly-ADP-ribosylation, which is required for DNA repair, regulation of apoptosis, and maintenance of genomic stability. This gene encodes the poly(ADP-ribosyl)transferase 3, which is preferentially localized to the daughter centriole throughout the cell cycle. Alternatively spliced transcript variants encoding different isoforms have been identified.

Gene Name: poly(ADP-ribose) polymerase family member 3

Alternative Symbols: IRT1, ARTD3, ADPRT3, ADPRTL2, ADPRTL3, PADPRT-3

Protein Name: poly [ADP-ribose] polymerase 3

Molekulargewicht: 59kDa

Gen-ID: 10039

NCBI Accession: NP_005476

UniProt: Q9Y6F1