LIME Antikörper (AA 281-296)

Produktnummer ABIN1839558

Produktdetails anti-LIME Antikörper

Target: LIME (LIME1) (Lck Interacting Transmembrane Adaptor 1 (LIME1))

Bindungsspezifität: AA 281-296

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser LIME Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Spezifität: LIME (Lck-interacting molecule) is a new raft-associated adaptor protein involved in regulation of T cell activation by coreceptors. LIME becomes tyrosine phosphorylated after cross-linking of the CD4 or CD8 coreceptors. Phospho-LIME associates with the Src family kinase Lck and its negative regulator, Csk. Ectopic expression of LIME in Jurkat T cells results in an increase of Csk in lipid rafts, increased phosphorylation of Lck and higher Ca2+ response to CD3 stimulation.

Aufreinigung: Purified

Immunogen: COOH-terminal peptide comprising residues 281-296 of the human LIME conjugated to keyhole limpet hemocyanin.

Type of Immunogen: Hapten

Klon: LIME-10

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

Target Species of Antibody: Human

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: PBS,  pH 7.4, 15 mM sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.

Details zu LIME

Target: LIME (LIME1) (Lck Interacting Transmembrane Adaptor 1 (LIME1))

Andere Bezeichnung: LIME1 / LIME (LIME1 Produkte)

Synonyme: LIME1 antikoerper, DKFZp459A158 antikoerper, LIME antikoerper, LP8067 antikoerper, dJ583P15.4 antikoerper, 2810038K19Rik antikoerper, RGD1562795 antikoerper, Lck interacting transmembrane adaptor 1 antikoerper, LIME1 antikoerper, Lime1 antikoerper

Hintergrund: Name/Gene ID: LIME1

Synonyms: LIME1, DJ583P15.4, Lck-interacting molecule, LIME, RP4-583P15.5, LP8067

Gen-ID: 54923

UniProt: Q9H400