PTPRM Antikörper

Produktnummer ABIN181182

Produktdetails anti-PTPRM Antikörper

Target: PTPRM (Protein Tyrosine Phosphatase, Receptor Type, M (PTPRM))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PTPRM Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Spezifität: This antibody detects Protein Tyrosine Phosphatase Mu (Family: Protein Phosphatase, Subfamily: R2A), internal domain of human.

Aufreinigung: Peptide immunogen affinity column.

Immunogen: PTPRM antibody was raised against synthetic peptide from internal domain of human PTPRM. Genename: PTPRM

Anwendungsinformationen

Applikationshinweise: Immunohistochemistry on paraffin embedded sections: 15 μg/mL. Antigen retrieval: Steam slides in 0.01 M sodium citrate buffer, pH 6.0, at 99-100C for 20 min. Remove from heat and let stand at room temperature in buffer for 20 min. Rinse in 1x TBS with Tween (TBST) for 1 min. at room temperature.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: PBS containing 0.09 % sodium azide as preservative

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody at 2 - 8 °C up to one month or in aliquots at -70 °C for longer.

Details zu PTPRM

Target: PTPRM (Protein Tyrosine Phosphatase, Receptor Type, M (PTPRM))

Andere Bezeichnung: PTPRM (PTPRM Produkte)

Synonyme: cb984 antikoerper, ptprm antikoerper, zgc:110218 antikoerper, PTPRM antikoerper, p-ptp-mu antikoerper, ptprl1 antikoerper, r-ptpu antikoerper, rptpm antikoerper, rptpu antikoerper, PTPRL1 antikoerper, R-PTP-MU antikoerper, RPTPM antikoerper, RPTPU antikoerper, hR-PTPu antikoerper, RPTPmu antikoerper, mKIAA4044 antikoerper, protein tyrosine phosphatase, receptor type, M, a antikoerper, protein tyrosine phosphatase, receptor type M antikoerper, protein tyrosine phosphatase, receptor type, M, b antikoerper, receptor-type tyrosine-protein phosphatase mu antikoerper, protein tyrosine phosphatase, receptor type, M antikoerper, ptprma antikoerper, PTPRM antikoerper, ptprmb antikoerper, ptprm antikoerper, LOC100550127 antikoerper, LOC100564083 antikoerper, Ptprm antikoerper

Hintergrund: PTP mu, a R2A receptor protein tyrosine phosphatase, is composed of an extracellular segment containing a MAM domain, an immunoglobulin domain and four fibronectin type III repeats, a transmembrane segment, and two intracellular protein phosphatase domains. PTP mu has been shown to affect cell-cell aggregation, regulate cardiac myocyte Kv1.5 channel expression, and promote neurite outgrowth of retinal ganglion cells. The human PTP mu gene is localized on chromosome 18pter-q11, a region with frequent abnormalities implicated in human cancer. PTP mu may be important in responses to pathological conditions associated with the loss of cell-cell interactions in the heart.Synonyms: PTPRL1, Protein-tyrosine phosphatase mu, R-PTP-mu, RPTPU, Receptor-type tyrosine-protein phosphatase mu

Gen-ID: 5797

NCBI Accession: NP_001098714

UniProt: P28827