Flow cytometry: neat - 1/10, use 10 μL of the suggested working dilution to label 10^6 cells. Membrane permeabilisation is required for this application. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
4 °C/-20 °C
Informationen zur Lagerung
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. This product is photosensitive and should be protected from light. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
Haltbarkeit
12 months
Target
Glucocorticoid Receptor (NR3C1)
(Nuclear Receptor Subfamily 3, Group C, Member 1 (Glucocorticoid Receptor) (NR3C1))
GR antikoerper, gcr antikoerper, grl antikoerper, xGR antikoerper, gccr antikoerper, gr antikoerper, zgc:113038 antikoerper, NR3C1 antikoerper, GCL antikoerper, LOC100302444 antikoerper, Gcr antikoerper, Grl antikoerper, Grl-1 antikoerper, Grl1 antikoerper, GRL antikoerper, GCCR antikoerper, GCR antikoerper, NO antikoerper, GR-A antikoerper, nr3c1 antikoerper, nuclear receptor subfamily 3 group C member 1 antikoerper, nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) antikoerper, nuclear receptor subfamily 3, group C, member 1 antikoerper, glucocorticoid receptor antikoerper, NR3C1 antikoerper, nr3c1 antikoerper, LOC100302444 antikoerper, Nr3c1 antikoerper
Hintergrund
Steroid receptors are ligand-dependent, intracellular proteins that stimulate transcription of specific genes by binding to specific DNA sequences following activation by the appropriate hormone. Glucocorticoids are a family of steroids necessary for the regulation of energy metabolism and the immune and inflammatory responses. These compounds exert their effect through their interaction with the glucocoticoid receptor (GR) and that complex's subsequent association with DNA. All normal mammalian tissues examined to date have been shown to contain glucocorticoid receptor.Synonyms: GR, GRL, NR3C1