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TNFRSF10B Antikörper (AA 388-407)
TNFRSF10B
Reaktivität: Human, Maus
WB, ICC, IHC (p), IF
Wirt: Kaninchen
Polyclonal
unconjugated
Produktnummer ABIN1733770
Produktdetails anti-TNFRSF10B Antikörper
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Target
Alle TNFRSF10B Antikörper anzeigen
TNFRSF10B
(Tumor Necrosis Factor Receptor Superfamily, Member 10b (TNFRSF10B))
Bindungsspezifität
Alle Epitope für TNFRSF10B Antikörper
AA 388-407
Reaktivität
Alle Reaktivitäten für TNFRSF10B Antikörper
Human, Maus
Wirt
Alle Wirte für TNFRSF10B Antikörper
Kaninchen
Klonalität
Alle Klonalitäten für TNFRSF10B Antikörper
Polyklonal
Konjugat
Alle Konjugate für TNFRSF10B Antikörper
Dieser TNFRSF10B Antikörper ist unkonjugiert
Applikation
Alle Applikationen für TNFRSF10B Antikörper
Western Blotting (WB), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)
Spezifität
Reacts with human and mouse DR5.
Aufreinigung
Purified
Immunogen
Synthetic peptide corresponding to aa 388- 407 of human DR5 precursor (accession no.AF012535)
Isotyp
IgG
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Discover our top product TNFRSF10B Primärantikörper
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Anwendungsinformationen
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Applikationshinweise
Working dilution: Optimal dilution should be determined by the end user. The following are guidelines only: WB(2 μg/mL) ICC(5 μg/mL)
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
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Format
Liquid
Konzentration
1 mg/mL
Buffer
PBS, pH 7.4
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung
Dilute in PBS or medium which is identical to that used in the assay system.
Lagerung
-20 °C
Informationen zur Lagerung
This antibody is stable for at least one (1) year at -20°C. Avoid multiple freeze-thaw cycles.
Details zu TNFRSF10B
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Target
TNFRSF10B
(Tumor Necrosis Factor Receptor Superfamily, Member 10b (TNFRSF10B))
Andere Bezeichnung
DR5 (TNFRSF10B Produkte )
Synonyme
TNFRSF10B antikoerper, dr5 antikoerper, cd262 antikoerper, killer antikoerper, trick2 antikoerper, trickb antikoerper, xDR-M1 antikoerper, xDR-M2 antikoerper, ztnfr9 antikoerper, trailr2 antikoerper, trick2a antikoerper, trick2b antikoerper, CD262 antikoerper, DR5 antikoerper, KILLER antikoerper, KILLER/DR5 antikoerper, TRAIL-R2 antikoerper, TRAILR2 antikoerper, TRICK2 antikoerper, TRICK2A antikoerper, TRICK2B antikoerper, TRICKB antikoerper, ZTNFR9 antikoerper, Ly98 antikoerper, MK antikoerper, tumor necrosis factor receptor superfamily, member 10b antikoerper, tumor necrosis factor receptor superfamily member 10b S homeolog antikoerper, tumor necrosis factor receptor superfamily member 10b L homeolog antikoerper, tumor necrosis factor receptor superfamily member 10b antikoerper, TNF receptor superfamily member 10b antikoerper, Tnfrsf10b antikoerper, TNFRSF10B antikoerper, tnfrsf10b.S antikoerper, tnfrsf10b.L antikoerper, tnfrsf10b antikoerper
Hintergrund
Apoptosis is induced by certain cytokines including TNF and Fas ligand in the TNF family through their death domain-containing receptors. TRAIL/Apo2L is a new member of the TNF family. A novel death domain containing receptor for TRAIL was recently identified and designated DR5, Apo2, TRAIL-R2, TRICK2, or KILLER by several independent laboratories. Like DR4, DR5 transcript is widely expressed in normal tissues and in many types of tumor cells. DR5 binds to TRAIL and mediates TRAIL induced cell death. Overexpression of DR5 induces apoptosis and activates NF-kB. Tumor necrosis factor receptor superfamily member 10B Death receptor 5 TNF-related apoptosis-inducing ligand receptor 2, TRAIL receptor 2, TRAIL-R2 CD_antigen: CD262 KILLER/DR5,TRICK2A, TRICK2B, TRICKB Gene name: TNFRSF10B, DR5, KILLER, TRAILR2, TRICK2, ZTNFR9
Gen-ID
8795
UniProt
O14763
Pathways
p53 Signalweg , Apoptose , Positive Regulation of Endopeptidase Activity
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