Band 3/AE1 Antikörper (pTyr21)

Produktnummer ABIN1713607

Produktdetails anti-Band 3/AE1 Antikörper

Target: Band 3/AE1 (SLC4A1) (Solute Carrier Family 4, Anion Exchanger, Member 1 (erythrocyte Membrane Protein Band 3, Diego Blood Group) (SLC4A1))

Bindungsspezifität: pTyr21

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Band 3/AE1 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))

Homologie: Human,Dog

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic phosphopeptide derived from human Band3 around the phosphorylation site of Tyr21

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu Band 3/AE1

Target: Band 3/AE1 (SLC4A1) (Solute Carrier Family 4, Anion Exchanger, Member 1 (erythrocyte Membrane Protein Band 3, Diego Blood Group) (SLC4A1))

Andere Bezeichnung: Band3 (SLC4A1 Produkte)

Synonyme: AE1 antikoerper, BND3 antikoerper, CD233 antikoerper, DI antikoerper, EMPB3 antikoerper, EPB3 antikoerper, FR antikoerper, RTA1A antikoerper, SW antikoerper, WD antikoerper, WD1 antikoerper, WR antikoerper, Ae1 antikoerper, Empb3 antikoerper, l11Jus51 antikoerper, ae1 antikoerper, band3 antikoerper, MGC152771 antikoerper, zgc:111889 antikoerper, zgc:152771 antikoerper, si:dz180g5.1 antikoerper, LOC100136769 antikoerper, slc4a1 antikoerper, wd1 antikoerper, bnd3 antikoerper, epb3 antikoerper, cd233 antikoerper, empb3 antikoerper, rta1a antikoerper, MGC80391 antikoerper, SLC4A1 antikoerper, BB3 antikoerper, EAT antikoerper, solute carrier family 4 member 1 (Diego blood group) antikoerper, solute carrier family 4 (anion exchanger), member 1 antikoerper, solute carrier family 4 (anion exchanger), member 1a (Diego blood group) antikoerper, Band 3 antikoerper, erythrocyte membrane protein band 4.1 like 3 antikoerper, solute carrier family 4 member 1 (Diego blood group) L homeolog antikoerper, solute carrier family 4 member 1 antikoerper, SLC4A1 antikoerper, Slc4a1 antikoerper, slc4a1a antikoerper, LOC100136769 antikoerper, EPB41L3 antikoerper, slc4a1.L antikoerper, slc4a1 antikoerper

Hintergrund:

Synonyms: SLC4A1, Band 3 phospho Y21, p-Band 3 phospho Y21, Solute carrier family 4 anion exchanger member 1, Solute carrier family 4 member 1, AE 1, AE1, Anion exchange protein 1, Anion exchanger 1, B3AT_HUMAN, Band 3, Band 3 anion transport protein, BND3, CD233, DI, Diego blood group, EMPB3, EPB3, Erythrocyte membrane protein band 3, Erythroid anion exchange protein, FR antibod, Froese blood group, RTA1A, Solute carrier family 4 member 1, SW antibody, Swann blood group, Waldner blood group, WD antibody, WD1, WR antibody, Wright blood group.

Background: Band 3, also designated AE1, is an erythrocyte membrane glycoprotein that contributes to cell stuctural integrity and mediates exchange of chloride and bicarbonate across the phospholipid bilayer. The diverse functions of the approximately 900 amino acid protein are mediated by two distinct domains. The amino terminal domain, also known as cdb3 for cytoplasmic domain of erthrocyte membrane band 3, acts as an attachment site for the erythrocyte skeleton by binding ankyrin. The carboxy-terminal, membrane-associated domain carries out exchange transport of anions. Degradation of band 3 can generate an aging antigen known as senescent cell antigen, or SCA, which is expressed on old cells and marks them for removal by the immune system. An isoform of band 3, which lacks the first 65 amino acids and does not bind ankryin, is expressed in kidney.

Gen-ID: 6521

UniProt: P02730